Pharmacokinetics, the study of the movement of chemicals within the body, is a vital tool in assessing the risk of exposure to environmental chemicals. This book--a collection of papers authored by experts in academia, industry, and government--reviews the progress of the risk-assessment process and discusses the role of pharmacokinetic principles in evaluating risk. In addition, the authors discuss software packages used to analyze data and to build models simulating biological phenomena. A summary chapter provides a view of trends in pharmacokinetic modeling and notes some prospective fields of study.
Table of Contents
|I. Introduction: The Problem and an Approach||1-24|
|II. Mathematical Modeling||25-62|
|III. Generalizations and Extrapolations||63-182|
|IV. Uncertainties: Integration with Risk Assessment and Resources||183-250|
|V. Poster Session||251-350|
|VI. Applications of Mathematical Modeling||351-428|
|VII. Summary: Prospectives and Future Directions||429-470|
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