Scaling Up Treatment for the Global AIDS Pandemic:

Challenges and Opportunities

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Size: 344 pages, 6x9

Publication Year:2005

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Authors:
James Curran, Haile Debas, Monisha Arya, Patrick Kelley, Stacey Knobler, and Leslie Pray, Editors, Committee on Examining the Probable Consequences of Alternative Patterns of Widespread Antiretroviral Drug Use in Resource-Constrained Settings
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Description:
An estimated forty million people carry the human immunodeficiency virus (HIV), and five million more become newly infected annually. In recent years, many HIV-infected patients in wealthy nations have enjoyed significantly longer, good-quality lives as a result of antiretroviral therapy ...
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Table of Contents
Select a link below to start reading online free!
Front Matter	i-xviii
Executive Summary	1-18	(skim)
1 Introduction	19-31	(skim)
2 Opportunities and Challenges	32-61	(skim)
3 Lessons Learned	62-88	(skim)
4 Principles of Scale-Up	89-133	(skim)
5 Managing Scale-Up of Antiretroviral Therapy	134-175	(skim)
6 The Path Forward	176-198	(skim)
Appendix A: Information Gathering Workshop Agenda	199-206	(skim)
Appendix B: Primer on Humanimmunodeficiency Virus, Acquired Immune Deficiency Syndrome and Antiretroviral Therapy	207-219	(skim)
Appendix C: Scaling Up Antiretroviral Therapy in Resource-Limited Settings: Treatment Guidelines for a Public Health Approach	220-278	(skim)
Appendix D: Human Ethical Issues Arising in ARV Scale-Up in Resource Constrained Settings	279-291	(skim)
Appendix E: Human Resource Requirements for Scaling Up Antiretroviral Therapy in Low-Resource Countries	292-308	(skim)
Appendix F: Glossary and Acronyms	309-317	(skim)
Appendix G: Committee and Staff Biographies	318-326	(skim)

Description

An estimated forty million people carry the human immunodeficiency virus (HIV), and five million more become newly infected annually. In recent years, many HIV-infected patients in wealthy nations have enjoyed significantly longer, good-quality lives as a result of antiretroviral therapy (ART). However, most infected individuals live in the poorest regions of the world, where ART is virtually nonexistent. The consequent death toll in these regions--especially sub-Saharan Africa--is begetting economic and social collapse.

To inform the multiple efforts underway to deploy antiretroviral drugs in resource-poor settings, the Institute of Medicine committee was asked to conduct an independent review and assessment of rapid scale-up ART programs. It was also asked to identify the components of effective implementation programs.

At the heart of the committee's report lie five imperatives:

Immediately introduce and scale up ART programs in resource-poor settings.
Devise strategies to ensure high levels of patient adherence to complicated treatment regimens.
Rapidly address human-resource shortages to avoid the failure of program implementation.
Continuously monitor and evaluate the programs to form the most effective guidelines and treatment regimens for each population.
Prepare to sustain ART for decades.

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