A significant medical event is expected in 1992: the first human use of a fully implantable, long-term cardiac assist device. This timely volume reviews the artificial heart program--and in particular, the National Institutes of Health's major investment--raising important questions.
The volume includes:
The committee also offers three mechanisms to aid in allocating research and development funds.
Table of Contents
|1. The Artificial Heart Program: Current Status and History||14-25|
|2. Total Artificial Hearts: Technological Potential and Research and Development Costs||26-43|
|3. Decisions for Future Research and Development||44-64|
|4. Clinical Effectiveness and Need for Long-Term Circulatory Support||65-84|
|5. Quality of Life and Mechanical Circulatory Support Systems||85-106|
|6. Cost-Effectiveness Analysis||107-120|
|7. The Appropriate Use of Technology||121-134|
|8. Ethical and Societal Issues||135-150|
|9. Roles of Government and Industry in Medical Technology Research, Development and Use||151-172|
|10. Conclusions and Recommendations||173-200|
|Appendix A: History and Methods of This Evaluation||201-204|
|Appendix B: A Chronology of the National Heart, Lung, and Blood Institute Artificial Heart Program and Related Events||205-210|
|Appendix C: Technological Opportunities and Barriers in the Development of Mechanical Circulatory Support Systems||211-250|
|Appendix D: Epidemiology of End-Stage Heart Disease||251-261|
|Appendix E: Assessing the Cost-Effectiveness of the Development and Use of the Total Artificial Heart||262-284|
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