(NAS Colloquium) Proteolytic Processing and Physiological Regulation

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Size: 108 pages, 8.5 x 11

Publication Year:1999

Authors:
Proceedings of the National Academy of Sciences, National Academy of Sciences
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Table of Contents
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Front Matter	i-vii
Proteolytic enzymes, past and future	10962-10963	(skim)
Caspase activation: The induced-proximity model	10964-10967	(skim)
Structural aspects of activation pathways of aspartic protease zymogens and viral 3C protease precursors	10968-10975	(skim)
The catalytic sites of 20S proteasomes and their role in subunit maturation: A mutational and crystallographic study	10976-10983	(skim)
The structure of the human ßII-tryptase tetramer: Fo(u)r better or worse	10984-10991	(skim)
Sonic hedgehog protein signals not as a hydrolic enzyme but as an apparent ligand for Patched	10992-10999	(skim)
Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes	11000-11007	(skim)
Kinetic stability as a mechanism for protease longevity	11008-11014	(skim)
Cysteine protease inhibitors as chemotherapy: Lessons from a parasite target	11015-11022	(skim)
How the protease thrombin talks to cells	11023-11027	(skim)
VanX, a bacterial D-alanyl-D-alanine dipeptidase: Resistance, immunity, or survival function?	11028-11032	(skim)
Chaperone rings in protein folding and degradation	11033-11040	(skim)
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood	11041-11048	(skim)
Cellular mechanisms of ß-amyloid production and secretion	11049-11053	(skim)
Reverse biochemistry: Use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue	11054-11061	(skim)

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