The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is falling short of its potential, and the IOM recommends changes that aim to transform the Cooperative Group Program into a dynamic system that efficiently responds to emerging scientific knowledge; involves broad cooperation of stakeholders; and leverages evolving technologies to provide high-quality, practice-changing research.
Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. https://doi.org/10.17226/12879.
Chapters | skim | |
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Front Matter | i-xviii | |
Executive Summary | 1-4 | |
Overview of Conclusions and Recommendations | 5-40 | |
1 Introduction | 41-76 | |
2 The Science of Developing Cancer Therapy | 77-120 | |
3 Operations, Oversight, and Funding of Cancer Clinical Trials | 121-190 | |
4 Physician and Patient Participation in Cancer Clinical Trials | 191-234 | |
Appendix A: Previous and Ongoing Analyses Undertaken by NCI | 235-258 | |
Appendix B: Committee Member and Staff Biographies | 259-274 | |
Acronyms | 275-278 | |
Glossary | 279-298 |
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