Kamioka et al. 1977

Lever response in macaques being threatened by another monkey exposed to electric shock; drugs administered to the aggressor monkey

Oxazepam (2 mg/kg s.c.), cloxazolam (0.5 mg/kg s.c.), chlordiazepoxide (2 mg/kg s.c.), diazepam (0.5 mg/kg s.c.) and CS-386 (0.5 mg/kg s.c.) increased suppressed response in monkeys being threatened by another monkey exposed to electric shock; drugs administered to the aggressor monkey did not increase suppressed response in the monkey being threatened. Some sedation and slight ataxia were observed at highest doses of diazepam and cloxazolam.

Vassout and Delini-Stula 1977

Electric foot shock-induced aggression in male rats

Chlordiazepoxide (1–3 mg/kg) did not alter aggression or motor behaviors.

Tsumagari et al. 1978

Electric foot shock-induced fighting in mice

Diazepam (1.8 mg/kg ED₅₀ i.p.) and Y-7131 (0.4 mg/kg ED₅₀ i.p.) reduced fighting episodes in mice. Motor activities (rotorod test) were diminished at higher doses of Y-7131 (2.1 mg/kg) and diazepam (5.3 mg/kg).

Fielding and Hoffman 1979

Electric foot shock-induced aggression in male mice

Clobazam (2.6 mg/kg ED₅₀ p.o.), chlordiazepoxide (14 mg/kg ED₅₀ p.o) and diazepam (0.16 mg/kg ED₅₀ p.o.) reduced percentage of animals fighting. No motor disturbances for any drug dose <25 mg/kg; ataxia at higher doses.

Delini-Stula and Vassout 1979

Electric foot shock-induced aggression in male rats

Diazepam (1–5 mg/kg i.p.) and oxazepam (10–50 mg/kg i.p.) reduced number of fighting bouts; similar doses of both chlordiazepoxide (2.5–10 mg/kg i.p.) and oxazepam (10–25 mg/kg i.p.) reduced locomotor activity.

Renzi 1982

Electric tail shock-induced aggression in pairs of restrained male mice tested 6 hours post injection

Chlordiazepoxide (2.5–5 mg/kg,i.p.) did not alter bites.

Jarvis et al. 1985

Electric tail shock-induced aggression in pairs of male mice

Chlordiazepoxide (2–16 mg/kg i.p.) dose dependently reduced target biting in confined mice.