The problems under investigation were as diverse as the preparations described above and for this reason it is difficult to designate areas of research with specific years in this period of Harry's career. There was, however, an emphasis on structure-function studies between 1960 and 1970. The roots for the latter began to grow rapidly after Michael V. L. Bennett joined the laboratory of neurophysiology in 1957. A few years after Harry introduced Bennett to electric fish and electroplaques (Scientific American, October 1960), the tempo of research on these preparations reached a peak. Interest in the field was also heightened by the publication of numerous papers dealing with the electrophysiological and structural properties of electroplaques by Harry, Mike, and colleagues.

An outgrowth of this work, in which Mike Bennett was also the primary investigator, was the study on the properties of cell-cell junctions. Both electrotonic and chemical synapses were investigated using electrophysiological and morphological approaches. The latter involved extensive electron microscopic investigations of both types of junctions, mainly in preparations from fish. This aspect of the work was carried out by George Pappas, a member of the Department of Anatomy and a longtime collaborator. These studies identified and classified cell-cell junctions, determined the mode of signalling between the cells, and emphasized the physiological significance of electrotonic junctions.

Structure-function studies on single muscle fibers also began during this period. The focus of these investigations was on the role played by transverse tubules, diads, and triads in the excitation-contraction-coupling (ECC) process. This work was initiated shortly after Lucien Girardier came to work² with Harry. Collaboration with Philip W. Brandt (then an assistant professor and currently a full professor