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Setting Priorities for
Clinical Practice Guidelines
Committee on Methods for Setting
Priorities for Guidelines Development
Marilyn I. Fielct, Editor
Division of Health Care Services
INSTITUTE OF MEDICINE
NATIONAL ACADEMY PRESS
Washington, D.C., 1995
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COMMITTEE ON METHODS FOR SETTING
PRIORITIES FOR GUIDELINES DEVELOPMENT
JEROME H. GROSSMAN, Chair, Chairman and Chief Executive Officer, The
New England Medical Center, Boston, Massachusetts
ROBERT A. BERENSON, Co-Founder and Co-Medical Director, National
Capital Preferred Provider Organization, Bethesda, Maryland
CATHERINE BORBAS, Executive Director, Healthcare Education and Research
Foundation, Inc., St. Paul, Minnesota
FRANCIS J. CROSSON, Associate Executive Director, The Permanente Group,
Oakland, California
SHELDON GREENFIELD, Senior Scientist, Primary Care Outcomes, Research
Institute, The New England Medical Center, Boston, Massachusetts
DAVID H. GUSTAFSON, Professor of Industrial Engineering and Preventive
Medicine, Center for Health Systems Research and Analysis, University of
Wisconsin, Madison, Wisconsin
WILLIAM L. MEDD, Internist, Oxford Hills Internal Medicine Group, Norway,
Maine
CHRISTINE A. MIASKOWSKI, Associate Professor, School of Nursing,
Department of Physiological Nursing, University of California, San Francisco,
San Francisco, California
WILLIAM L. ROPER,* Senior Vice President and Chief Medical Officer, The
Prudential Health Care System, Atlanta, Georgia
LOUISE B. RUSSELL,* Research Professor of Economics and Chair of Health
Care Policy Division, Institute for Health, Health Care Policy, and Aging
Research, Rutgers University, New Brunswick, New Jersey
RICHARD N. SHIFFMAN, Assistant Professor of Pediatrics, Center for Medical
Informatics, Yale School of Medicine, New Haven, Connecticut
LINDA JOHNSON WHITE, Director, Department of Scientific Policy,
American College of Physicians, Philadelphia, Pennsylvania
STUDY STAN
Marilyn J. Field, Study Director
Kathleen N. Lohr, Director, Division of Health Care Services
Nina Spruill, Financial Associate
Donna D. Thompson, Administrative Assistant
H. Donald Tiller, Administrative Assistant
*Member, Institute of Medicine
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Acknowledgments
The committee wants to acknowledge those who assisted it in preparing this
report. Staff from several organizations informed the committee about their
priority-setting processes. They include David Eddy and Margaret Gordon from
Kaiser Permanente Southern California, Carolyn DiGuiseppe from the U.S.
Preventive Services Task Force, Thomas Holohan from the Office of Health
Technology Assessment, Susan Horn from Intermountain Health Care, Gregory
Gifford of the State of Minnesota, and John Ferguson at the National Institutes
of Health. The authors of three commissioned papers, Susan Horn, Troyen
Brennan, and Steven Warunan, helped stimulate discussion at the committee's
August workshop, and all the participants in that meeting (see Appendix B)
helped the committee develop its thinking.
At the Agency for Health Care Policy and Research, David Lanier provided
information and documents that increased the committee's understanding of the
agency's procedures in selecting topics for guidelines development. Stephen
King, the former director of the Office of the Forum on Quality and
Effectiveness in Health Care, contributed background information on the
organization's early activities. Jarrett Clinton and Clifton Gaus, the former and
current directors ofthe agency, encouraged the committee to think broadly about
its work.
Molla Donaldson, who directed a 1992 Institute of Medicine study on
priority setting for technology assessment, provided valuable insights into the
analyses and recommendations from that study. During the summer of 1994,
Jane Deng, an American Medical Student Association intern, helped in myriad
ways including developing legislative and regulatory histories. The successful
completion of the study also reflects the contributions of Kathleen Lohr, Claudia
Carl, Nina Spruill, Michael Edington, and Donna Thompson.
v
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Contents
SCARY
1 INTRODUCTION
Background, 13
Committee Approach, 15
Priority Setting in Other Organizations, 19
Overview of Report, 25
CRITERIA FOR TOPIC SELECTION
Current Criteria for Guidelines Topics, 27
Current Criteria for Technology Assessment, 30
Differences in Criteria for Guidelines
and Technology Assessment, 31
Toward Common Criteria?, 32
Additional Criteria, 36
The Relative Importance of Individual Criteria, 37
Procedures for Applying Criteria, 38
Reassessment of Existing Guidelines, 41
3 PROCEDURES FOR PRIORITY SETTING
Forum and OHTA Priority-Setting Procedures, 46
Toward Common Procedures?, 50
Process Modifications: Improving the Use of
Expert Judgment, 51
Development of a Procedure Manual, 56
· .
V11
11
27
45
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viii
CONTENTS
4 FUTURE DIRECTIONS FOR PRIORITY SETTING
Review of Findings and Recommendations on Priority Setting, 57
Definition of Guidelines Topics, 61
National and Local Guidelines, 63
Future Roles for AHCPR, 64
Conclusion, 70
REFERENCES
APPENDIXES
57
73
A Setting Priorities for Health Technology Assessment: A Model
Process, Executive Summary, 77
B Workshop on Setting Priorities for Practice Guidelines, 93
C Methods for Setting Priorities for Guidelines Development: Medical
Malpractice, 99
Troyen A. Brennan
D National Guidelines and Local Action: Priority-Setting for the
Development of Research-Based Protocols at Intermountain Health
Care, 111
Susan D. Horn
E The Development of Clinical Guidelines for Primary Care Practice:
A Systems Approach, 133
Steven A. Wartman
F Examples of Questionnaires for Use in Priority Setting, 151
G Committee Biographies, 157
INDEX
Tables
1.1
2.2
2.3
TABLES AND FIGURES
AHCPR Guidelines Published and Under Development as of
November 1,1994, 15
Legislative Criteria for Selection of Guidelines Topics for AHCPR's
Fonda on Quality and Effectiveness in Health Care, from P.L. 102
239 (1989) and P.L. 102-410 (1992), 28
Priority-setting Criteria Specified by the Forum, 29
Criteria for Setting Priorities for Selecting OHTA Technology
Assessment Topics, 31
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