| ||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||
| Copyright © 2010. National Academy of Sciences. All rights reserved. Terms of Use and Privacy Statement |
Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page 202
References
ABT Associates, Inc. 1996. An Evaluation of the NSF Science and Technology Centers (STC)
Program. Cambridge, MA: Center for Science and Technology Policy Studies.
AIP Center for History of Physics. 1992. AIP Study of Multi-Institutional Collaborations.
Phase I: High-Energy Physics. Report Number 1: Summary of Project and Findings:
Project Recommendations. College Park, MD: American Institute of Physics.
Abbott A. 2001. Workshop prepares ground for human proteome project. Nature 413~6858~:
763.
Adam D. 2001a. Database of molecular probes set to boost chemical genetics. Nature
411~6840~:873.
Adam D. 2001b. Genetics group targets disease markers in the human sequence. Nature
412(6843~:105.
Aker J. 2002. Access to intellectual property under Bayh/Dole subject of Markey GAO
investigation request. Washington, DC: Washington Fax.
Alper J. 1999. From the bioweapons trenches, new tools for battling microbes. Science
284~5421~:1754-5.
Anderson PW. 1999. Why do they leave physics? Physics Today 52~9~: 11.
Austin R. 2002. Project management and discovery. Science Next Wave September 13. See
.
Bar-Shalom A, Cook-Deegan R. 2002. Patents and innovations in cancer therapeutics: Les-
sons from cell pro. The Millbank Quarterly 80~4~.
Barinaga M. 2000. Scientific community. Soft money's hard realities. Science 289~5487~:2024-8.
Blumenthal D, Campbell KG, Anderson MS, Causino N. Louis KS. 1997. Withholding re-
search results in academic life science. Evidence from a national survey of faculty.
JAMA 277~15~:1224-8.
Boahene AK. 2002. Patented genetic sequences would be available to researchers under
Rivers bill. Washington, DC: Washington Fax.
Brunak S. Danchin A, Hattori M, Nakamura H. Shinozaki K, Matise T. Preuss D. 2002.
Nucleotide sequence database policies. Science 298~5597~:1333.
Burley SK. 2000. An overview of structural genomics. Nat Struct Biol 7 Suppl:932-4.
202
OCR for page 203
REFERENCES
203
Campbell KG, Clarridge BR, Gokhale M, Birenbaum L, Hilgartner S. Holtzman NA, Blu-
menthal D. 2002. Data withholding in academic genetics: evidence from a national
survey. JAMA 287:473-80.
Cancer Letter. 2001. NCI, NIGMS To Support Synchotron Beamlines. The Cancer Letter 27~42)
November 16. Washington, DC: Cancer Letter Publicatons.
Check E. 2002. NIH ponders issues of scale in protein push. Nature 417~6885~:107.
Chicurel M. 2001. Faster, better, cheaper genotyping. Nature 412~6847~:580-2.
Clarke J. Piccolo J. Stanton B. Tyson K. 2000. Patent Pools: A Solution to the Problem of
Access in Biotechnology Patents. Washington, DC: United States Patent and Trade-
mark Office.
Cohen J. 1999. Philanthropy's rising tide lifts science. Science 286~5438~:214-23.
Cohen J. 2002. Public health. Gates Foundation rearranges public health universe. Science
295~5562~:2000.
Cook-Deegan RM. 1994. The Gene Wars: Science, Politics, and the Human Genome. New
York: W.W. Norton & Company.
Couzin J. 2002a. Genomics. New mapping project splits the community. Science 296~5572~:
1391-3.
Couzin J. 2002b. Human genome. HapMap launched with pledges of $100 million. Science
298~5595~:941-2.
Couzin J. Enserink M. 2002. Women's health. More questions about hormone replacement.
Science 298~5595~:942.
Crow M, Bozeman B. 2001. Limited By Design: R&D Laboratories in the U.S. National
Innovation System. New York: Columbia University Press.
Culliton B. 1974. Virus cancer program: Review panel stands by criticism. Science 184~4133~:
143-5.
Davies K. 2001. Cracking the Genome: Inside the Race to Unlock Human DNA. New York:
Free Press.
Davis BD. 1990. The human genome and other initiatives. Science 249~4967~:342-3.
Davis M. 2000. Sorting basic research into disease categories is a nightmare for NIH admin-
istrators, yet patient advocates, many in Congress, think in those terms. Washington,
DC: Washington Fax.
DeVita VT, Goldin A. 1984. Therapeutic research in the National Cancer Institute. NIH: An
account of research in its laboratories and clinics. Orlando, FL: Academic Press.
Ducor P. 1997. Are patents and research compatible? Nature 387~6628~:13-4.
Dulbecco R. 1986. A turning point in cancer research: sequencing the human genome. Sci-
ence 231~4742~:1055-6.
Edwards M. 1996. 360 Feedback: The Powerful New Model for Employee Assessment and
Performance Improvement. New York: Amacom Books.
Eisenberg RS. 1997. Chapter 2. National Research Council. Intellectual Property Rights and
the Dissemination of Research Tools in Molecular Biology. Washington, DC: National
Academy Press.
Eisenberg RS. 2000. Genomics in the public domain: strategy and policy. Nat Rev Genet
1~1~:70-4.
Encyclopedia Brittanica. 2003. See .
Enserink M.2002a. Epidemiology. Despite safety concerns, U.K. hormone study to proceed.
Science 297~5581~:492.
Enserink M. 2002b. Women's health. The vanishing promises of hormone replacement.
Science 297~5580~:325-6.
Ergenzinger E, Spruill M. 2003. Basic science in U.S. universities can infringe patents. The
Scientist 17~5~:43.
OCR for page 204
204
LARGE-SCALE BIOMEDICAL SCIENCE
Freeman R. Weinstein E, Marincola E, Rosenbaum J. Solomon F. 2001. Careers. Competition
and careers in biosciences. Science 294~5550~:2293-4.
Funding First Collection. 2000. Exceptional Returns: The Economic Value of America's In-
vestment in Medical Research. New York: Funding First.
Galison P. Hevly B. 1992. Big Science: The Growth of Large-Scale Research. Stanford:
Stanford University Press.
Gallo RC. 1999. Thematic review series. XI: Viruses in the origin of human cancer. Introduc-
tion and overview. Proc Assoc Am Physicians 111:560-2.
Gallo RC, Mann D, Broder S. Ruscetti FW, Maeda M, Kalyanaraman VS, Robert-Guroff M,
Reitz MS Jr. 1982. Human T-cell leukemia-lymphoma virus (HTLV) is in T but not B
lymphocytes from a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci U S A
79:5680-3.
Gershon D. 2000. Vaccine centres unite specialists in the battle against infectious diseases.
Nature 408~6813~:753-4.
Gillespie G. Chubin D, Kurzon G. 1985. Experience with the NIH peer review: researcher's
cynicism and desire for change. Science, Technology, and Human Value 10:44-53.
Glanz J. 1998. Careers: Young physicists despair of tenured jobs. Science 279~5354~:1128.
Golde CM, Dore, TM. 2001. At Cross Purposes: What the Experiences of Doctoral Students
Reveal about Doctoral Education (~. Philadelphia, PA: A re-
port prepared for The Pew Charitable Trusts.
Goldberg S. 1995. Big Science: Atomic Bomb Research and the Beginnings of High Energy
Physics. Seattle: History of Science Society.
Goldman E, Marshall E. 2002. Research funding. NIH grantees: where have all the young
ones gone? Science 298~5591~:40-1.
Green W. 1995. Two Cheers for Democracy: Science and Technology Politics. New York:
Center for Science, Policy, and Outcomes.
Greenberg DS. 2001. Science, Money, and Politics: Political Triumph and Ethical Erosion.
Chicago: University of Chicago Press.
Gross CP, Anderson GF, Powe NR. 1999. The relation between funding by the National
Institutes of Health and the burden of disease. N Engl J Med 340:1881-7.
Hackett E. 1987. The plight of academic "marginals". The Scientist 1~18~:13.
Hafner L. 2001. Rat genome project shifts to whole-genome shotgun, adds pioneer Celera.
Washington, DC: Washington Fax.
Hafner L. 2002. Rigorous OMB performance measures will be used to frame agency budget
proposals for FY 2004. Washington, DC: Washington Fax.
Haley S. 2000. The public and most of Congress believe there is a direct relationship be-
tween investment and cure, warns AAAS fellow. Washington, DC: Washington Fax.
Haley S. 2001. Kirschstein tells how NIH is adapting to the evolving multidisciplinary
research model. Washington, DC: Washington Fax.
Haywood HL. 1923. Freemasonry and the Guild System. The Builder.
Heilbron JL, Kevles DJ. 1988. Finding a policy for mapping and sequencing the human
genome: Lessons from the history of particle physics. Minerva 26:299-314.
Heinig SJ, Quon AS, Meyer RE, Korn D. 1999. The changing landscape for clinical research.
Acad Med 74:726-45.
Heller MA, Eisenberg RS. 1998. Can patents deter innovation? The anticommons in bio-
medical research. Science 280~5364~:698-701.
Helmuth L. 2001. Genome research: map of the human genome 3.0. Science 293~5530~:
583-5.
Hendler J. 2003. Communication. Science and the semantic web. Science 299~5606~:520-1.
Henry MR, Cho MK, Weaver MA, Merz JF. 2002. Genetics. DNA patenting and licensing.
Science 297~5585~:1279.
OCR for page 205
REFERENCES
205
Institute of Medicine. 1994. Careers in Clinical Research: Obstacles and Opportunities.
Washington, DC: National Academy Press.
Institute of Medicine. 1996. Resource Sharing in Biomedical Research. Washington, DC:
National Academy Press.
Institute of Medicine. 1998. Scientific Opportunities and Public Needs: Improving Priority
Setting and Public Input at the National Institutes of Health. Washington, DC: Na-
tional Academy Press.
Institute of Medicine. 2000. Summary of the June 2000 Meeting of the Clinical Research
Round Table. Washington, DC: National Academy Press.
Jenkins SC. 2002a. PCAST Bayh-Dole assessment likely will address investment recovery.
Washington, DC: Washington Fax.
Jenkins SC. 2002b. Proactively shaping control arrangements can ensure data access, Duke's
Reichman tells science community. Washington, DC: Washington Fax.
Jenkins SC. 2003a. President's science and technology council to advise administration on
tech transfer policy in March. Washington, DC: Washington Fax.
Jenkins SC. 2003b. Two percent NIH FY 2000 budget increase would reduce new grants by
1000 FASEB says. Washington, DC: Washington Fax.
Kaiser J. 2001. Bioinformatics. Hughes to build own tech research center. Science 291~5505~:
803.
Kaiser J. 2002. Proteomics. Public-private group maps out initiatives. Science 296~5569~:827.
Kevles DJ, Hood L. 1992. The Code of Codes: Scientific and Social Issues in the Human
Genome Project. Cambridge, MA: Harvard University Press.
Korn D, Rich RR, Garrison HH, Golub SH, Hendrix MJ, Heinig SJ, Masters BS, Turman RJ.
2002. Science policy. The NIH budget in the "postdoubling" era. Science 296~5572~:1401-
2.
Kyd J. 2000. New PTO guidelines released. Added utility requirement may cause problems
for biomedical researchers. Washington, DC: Washington Fax.
Lake G. Hood LE. 2001. Big computing comes to biology. Nature Yearbook of Science and
Technology. Washington, DC: Nature Publishing Group: 82-5.
Lander ES, Linton LM, Birren B. Nusbaum C, Zody MC, Baldwin J. Devon K, Dewar K,
Doyle M, FitzHugh W. Funke R. Gage D, Harris K, Heaford A, Howland J. Kann L,
Lehoczky J. LeVine R. McEwan P. McKernan K, Meldrim J. Mesirov JP, Miranda C,
Morris W. Naylor J. Raymond C, Rosetti M, Santos R. Sheridan A, Sougnez C, Stange-
Thomann N. Stojanovic N. Subramanian A, Wyman D, Rogers J. Sulston J. Ainscough
R. Beck S. Bentley D, Burton J. Clee C, Carter N. Coulson A, Deadman R. Deloukas P.
Dunham A, Dunham I, Durbin R. French L, Grafham D, Gregory S. Hubbard T. Hum-
phray S. Hunt A, Jones M, Lloyd C, McMurray A, Matthews L, Mercer S. Milne S.
Mullikin JC, Mungall A, Plumb R. Ross M, Shownkeen R. Sims S. Waterston RH,
Wilson RK, Hillier LW, McPherson JD, Marra MA, Mardis ER, Fulton LA, Chinwalla
AT, Pepin KH, Gish WR, Chissoe SL, Wendl MC, Delehaunty KD, Miner TL, Dele-
haunty A, Kramer JB, Cook LL, Fulton RS, Johnson DL, Minx PJ, Clifton SW, Hawkins
T. Branscomb E, Predki P. Richardson P. Wenning S. Slezak T. Doggett N. Cheng JF,
Olsen A, Lucas S. Elkin C, Uberbacher E, Frazier M, Gibbs RA, Muzny DM, Scherer
SE, Bouck JB, Sodergren EJ, Worley KC, Rives CM, Gorrell JH, Metzker ML, Naylor
SL, Kucherlapati RS, Nelson DL, Weinstock GM, Sakaki Y. Fujiyama A, Hattori M,
Yada T. Toyoda A, Itoh T. Kawagoe C, Watanabe H. Totoki Y. Taylor T. Weissenbach
J. Heilig R. Saurin W. Artiguenave F. Brottier P. Bruls T. Pelletier E, Robert C, Wincker
P. Smith DR, Doucette-Stamm L, Rubenfield M, Weinstock K, Lee HM, Dubois J.
Rosenthal A, Platzer M, Nyakatura G. Taudien S. Rump A, Yang H. Yu J. Wang J.
Huang G. Gu J. Hood L, Rowen L, Madan A, Qin S. Davis RW, Federspiel NA, Abola
AP, Proctor MJ, Myers RM, Schmutz J. Dickson M, Grimwood J. Cox DR, Olson MV,
OCR for page 206
206
LARGE-SCALE BIOMEDICAL SCIENCE
Kaul R. Raymond C, Shimizu N. Kawasaki K, Minoshima S. Evans GA, Athanasiou M,
Schultz R. Roe BA, Chen F. Pan H. Ramser J. Lehrach H. Reinhardt R. McCombie WR,
de la Bastide M, Dedhia N. Blocker H. Hornischer K, Nordsiek G. Agarwala R. Aravind
L, Bailey JA, Bateman A, Batzoglou S. Birney E, Bork P. Brown DG, Burge CB, Cerutti
L, Chen HC, Church D, Clamp M, Copley RR, Doerks T. Eddy SR, Eichler EE, Furey
TS, Galagan J. Gilbert JG, Harmon C, Hayashizaki Y. Haussler D, Hermjakob H. Ho-
kamp K, Jang W. Johnson LS, Jones TA, Kasif S. Kaspryzk A, Kennedy S. Kent WJ,
Kitts P. Koonin EV, Korf I, Kulp D, Lancet D, Lowe TM, McLysaght A, Mikkelsen T.
Moran JV, Mulder N. Pollara VJ, Ponting CP, Schuler G. Schultz J. Slater G. Smit AF,
Stupka E, Szustakowski J. Thierry-Mieg D, Thierry-Mieg J. Wagner L, Wallis J. Wheeler
R. Williams A, Wolf YI, Wolfe KH, Yang SP, Yeh RF, Collins F. Guyer MS, Peterson J.
Felsenfeld A, Wetterstrand KA, Patrinos A, Morgan MJ, Szustakowki J. de Jong P.
Catanese JJ, Osoegawa K, Shizuya H. Choi S. Chen YJ. 2001. Initial sequencing and
analysis of the human genome. Nature 409~6822~:860-921.
Lawler A. 2003. University-industry collaboration. Last of the big-time spenders? Science
299(5605):330-3.
Lazear EP, Rosen S. 1981. Rank order tournaments as optimal labor contracts. J Polit Econ
89:841-864.
Lekowski W. 1999. Research results can be measured for performance review, says CO-
SEPUP. Even basic research can be measured according to certain standards. Wash-
ington, DC: Washington Fax.
Levin R. Klevorick A, Nelson R. Winter S. 1987. Appropriating the returns from industrial
research and development. Brookings Papers on Economic Activity. Brookings Insti-
tute, Washington, DC: 783-832.
Lewis R. 2001. News A personal view of genomics. The Scientist 15~23~:10.
Loder N. 2000. Celera's shotgun approach puts Drosophila in the bag. Nature 403~6772~:
817.
Longfellow D. 2000. Introductory Remarks. Estrogens As Endogenous Carcinogens in the
Breast and Prostate. Conference Proceedings. Chantilly, Virginia, USA. March 15-17,
1998. Journal of the National Cancer Institute Monographs 27:13-5.
Macilwain C. 2000. World leaders heap praise on human genome landmark. Nature 405~6790~:
983-5.
Malakoff D. 1999. Military research: Pentagon agency thrives on in-your-face science. Sci-
ence 285~5433~:1476-9.
Malakoff D. 2001. Functional genomics. Pathogen researchers get help from TIGR. Science
294~5549~:2069-70.
Malakoff D. 2003. Intellectual property. Universities ask Supreme Court to reverse patent
ruling. Science 299~5603~:26-7.
Marshall E. 1997. Too radical for NIH? Try DARPA. Science 275~5301~:744-6.
Marshall E. 1999. New NIH rules promote greater sharing of tools and materials. Science
286~5449~:2430-1.
Marshall E. 2000. Genomics. Public-private project to deliver mouse genome in 6 months.
Science 290~5490~:242-3.
Marshall E. 2001. Genome sequencing. Celera assembles mouse genome; public labs plan
new strategy. Science 292~5518~:822.
Marshall E. 2002a. Intellectual property. DuPont ups ante on use of Harvard's OncoMouse.
Science 296~5571~:1212.
Marshall E. 2002b. Genome sequencing. Public group completes draft of the mouse. Science
296~5570~:1005.
Marshall E. 2002c. Data sharing. DNA sequencer protests being scooped with his own data.
Science 295~5558~:1206-7.
OCR for page 207
REFERENCES
207
Maurer SM, Hugenholtz PB, Onsrud HI. 2001. Intellectual property. Europe's database ex-
periment. Science 294~5543~:789-90.
McGeary and Burstein. 1999. Sources of Cancer Research Funding in the United States.
Washington, DC: Institute of Medicine.
McGeary and Merrill. 1999. Recent trends in federal spending on scientific and engineering
research: Impacts on research fields and graduate training. (Appendix A). STEP Board.
Securing America's Industrial Strength. Washington, DC: National Academy Press.
Mervis J. 2002. Research centers. Science with an agenda: NSF expands centers program.
Science 297~5581~:506-9.
Metheny B. 2002. NIH reorganization should be thematic, relevant to the public perception
of medical research, panelists advise. Washington, DC: Washington Fax.
Nathan D.1997. NIH Director's Panel on Clinical Research Report to the Advisory Commit-
tee to the NIH Director. Bethesda, MD: National Institutes of Health.
Nathanson KL, Shugart YY, Omaruddin R. Szabo C, Goldgar D, Rebbeck TR, Weber BL.
2002. CGH-targeted linkage analysis reveals a possible BRCA1 modifier locus on chro-
mosome 5q. Hum Mol Genet 11:1327-32.
National Academy of Public Administration (NAPA). 1995. National Science Foundation's
Science and Technology Centers: Building an Interdisciplinary Research Program.
Washington, DC: NAPA.
National Academy of Sciences. 1999. Evaluating Federal Research Programs: Research and
the Government Performance and Results Act. Washington, DC: National Academy
Press.
National Academy of Sciences. 2001. Implementing the Government Performance and Re-
sults Act for Research: A Status Report. Washington, DC: National Academy Press.
National Cancer Advisory Board. 1974. Report of the Ad Hoc Review Committee of the
Virus Cancer Program. Bethesda, MD: National Cancer Institute.
National Cancer Advisory Board: Ad Hoc Working Group on the NCI Intramural Research
Program. 1995. A Review of the Intramural Program of the NCI (Bishop Calabresi
Report). Bethesda, MD: National Cancer Institute.
National Cancer Advisory Board. Report of the P30/P50 Ad Hoc Working Group. 2003.
Advancing Translational Cancer Research: A Vision of the Cancer Center and SPORE
Programs of the Future. Bethesda, MD: National Cancer Institute.
National Institutes of Health. 1998. Report of the NIH Working Group on Research Tools.
Bethesda, MD: National Institutes of Health.
National Research Council. 1988. Mapping and Sequencing the Human Genome. Washing-
ton, DC: National Academy Press.
National Research Council. 1994a. A Space Physics Paradox. Washington, DC: National
Academy Press.
National Research Council.1994b. Sharing Laboratory Resources: Genetically Altered Mice.
Washington, DC: National Academy Press.
National Research Council, Committee on Criteria for Federal Support of Research and
Development. 1995. Allocating Federal Funds for Science and Technology. Washing-
ton, DC: National Academy Press.
National Research Council, COSEPUP. 1996. An assessment of the National Science Found-
ation's Science and Technology Centers Program. Washington, DC: National Acad-
emy Press.
National Research Council. 1997. Intellectual Property Rights and the Dissemination of
Research Tools in Molecular Biology. Washington, DC: National Academy Press.
National Research Council. 1998a. Trends in the Early Careers of Life Scientists. Washing-
ton, DC: National Academy Press.
OCR for page 208
208
LARGE-SCALE BIOMEDICAL SCIENCE
National Research Council.1998b. Serving Science and Society in the New Millenium. Wash-
ington, DC: National Academy Press.
National Research Council. 1999. A Question of Balance: Private Rights and the Public
Interest in Scientific and Technical Databases. Washington, DC: National Academy
Press.
National Research Council. 2000. Enhancing the Postdoctoral Experience for Scientists and
Engineers. Washington, DC: National Academy Press.
National Research Council. 2001a. Trends in Federal Support of Research and Graduate
Education. Washington DC: National Academy Press.
National Research Council. 2001b. Physics in a New Era. Washington, DC: National Acad-
emy Press.
National Research Council. 2003. Sharing Publication-Related Data and Materials: Respon-
sibilities of Authorship in the Life Sciences. Washington, DC: The National Academies
Press.
National Science Foundation. 2002. Science and Engineering Indicators 2002. Arlington,
VA: National Science Foundation.
Norberg A, O'Neill JE. 1996. Transforming Computer Technology: Information Processing
for the Pentagon, 1962-86. Baltimore: Johns Hopkins University Press.
Office of Technology Assessment. 1991. Federally Funded Research: Decisions for a De-
cade. Washington, DC: OTA.
Pennisi E. 1998. DNA sequencers' trial by fire. Science 280~5365~:814-7.
Pennisi E. 1999. Fruitfly researchers sign pact with Celera. Science 283~5403~:767.
Pennisi E. 2000a. Genomics. Fruit fly genome yields data and validation. Science 287~5457~:
1374.
Pennisi E. 2000b. Genomics. Mouse sequencers take up the shotgun. Science 287~5456~:1179,
1181.
Pennisi E. 2002a. Genomics. Genome centers push for polished draft. Science 296~5573~:
1600-1.
Pennisi E. 2002b. Human genome project. Genome institute wrestles mightily with its fu-
ture. Science 298~5599~:1694-5.
Pennisi E. 2003. Reaching their goals early, sequencing labs celebrate. Science 300~5618~:409.
Pressman L. 2002. AUTM Licensing Survey: FY 2000. See .
Rettig RA. 1977. Cancer Crusade: The Story of the National Cancer Act of 1971. Princeton,
NJ: Princeton University Press.
Roberts L. 2002. Genome research. A tussle over the rules for DNA data sharing. Science
298(5597~:1312-3.
Rossouw JE, Finnegan LP, Harlan WR, Pinn VW, Clifford C, McGowan JA.1995. The evolu-
tion of the Women's Health Initiative: perspectives from the NIH. J Am Med Womens
Assoc 50~2~:50-5.
Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson
RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J. 2002. Risks and
benefits of estrogen plus progestin in healthy postmenopausal women: principal re-
sults from the Women's Health Initiative randomized controlled trial. JAMA
288~3~:321-33.
Rowen L, Mahairas G. Hood L. 1997. Sequencing the human genome. Science 278~5338~:
605-7.
Sachidanandam R. Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G. Sherry S.
Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning
Z. Rogers J. Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B. Cook L, Davenport
R. Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B. Schaffner S.
Van Etten WJ, Reich D, Higgins J. Daly MJ, Blumenstiel B. Baldwin J. Stange-Thomann
OCR for page 209
REFERENCES
209
N. Zody MC, Linton L, Lander ES, Atshuler D. 2001. A map of human genome se-
quence variation containing 1.42 million single nucleotide polymorphisms. Nature
409(6822):928-33.
Science and Government Alert. Zerhouni presents road map for NIH's future to his advi-
sors. December 13, 2002. Washington, DC.
ScienceScope. 2000. Relishing victory. Science 288~5474~:2299.
ScienceScope. 2002. Science 295~5562~:1991.
Service RF. 2000. Proteomics. Can Celera do it again? Science 287~5461~:2136-8.
Service RF. 2001a. Proteomics. A Proteomics upstart tries to outrun the competition. Science
294~5549~:2079-80.
Service RF. 2001b. Proteomics. Gene and protein patents get ready to go head to head.
Science 294~5549~:2082-3.
Service RF. 2001c. Proteomics. High-speed biologists search for gold in proteins. Science
294~5549~:2074-7.
Service RF. 2002. Structural genomics. Tapping DNA for structures produces a trickle. Sci-
ence 298~5595~:948-50.
Shine KI. 1998. Encouraging clinical research by physician scientists. JAMA 280:1442-4.
Smaglik P. 2000. Genomics initiative to decipher 10,000 protein structures. Nature 407~6804~:
549.
Smaglik P. 2001. Building Protein Pipelines. Nature (Naturejobs).413~6851~:4-6.
Softcheck J. 2002. Federal R&D at $111.8 billion in President's FY 03 budget proposal,
Marburger says. Washington, DC: Washington Fax.
Spieler R. 2002. NIH works to protect research data from incursion while pressing research-
ers to share among themselves. Washington, DC: Washington Fax.
Stephan PE, Black G. 2001. Bioinformatics: Emerging opportunities and emerging gaps, In:
Capitalizing on New Needs and New Opportunities: Government Industry Partner-
ships in Biotechnology and Information Technologies. Washington, DC: National
Academy Press.
Stevens RC, Yokoyama S. Wilson IA. 2001. Global efforts in structural genomics. Science
294~5540~:89-92.
Stockwell BR. 2000. Chemical genetics: ligand-based discovery of gene function. Nat Rev
Genet 1~2~:116-25.
Sulston J. Ferry G. 2002. The Common Thread: A Story of Science, Politics, Ethics, and the
Human Genome. 1st ed. Washington, DC: Joseph Henry Press.
Task Force on the Future of Clinician Scientists at UCSF. 2000. The Future of Clinician
Scientists: Initial Report and Recommendations. San Francisco, CA: UCSF.
Thomas P. Gilbert D. 2002. Opinion. Beyond Serendipity. The Scientist 16~23~:12.
Thorner B. 1997. Trading patent rights for research tools: What's at stake? Nat Biotechnol
15~10~:1024-27.
UCOP (University of California Office of the President). 1997. Tenure review.
U.S. Congress General Accounting Office. 1999. August. Technology Transfer: Reporting
Requirements for Federally Sponsored Inventions Need Revision: Washington, DC:
General Accounting Office.
U.S. Department of Health, Education, and Welfare. 1966. Report of the Secretary's Advi-
sory Committee on the Management of National Institutes of Health Research Con-
tracts and Grants. (Ruina Report). Washington, DC: Government Printing Office.
U.S. Department of Health, Education, and Welfare. 1973. National Cancer Program. Re-
port of the National Cancer Advisory Board. Washington, DC: Government Printing
Office. Notes: DHEW Publication No. (NIH) 74-471.
OCR for page 210
210
LARGE-SCALE BIOMEDICAL SCIENCE
U.S. Department of Health and Human Services, Office of the Inspector General. 1994. NIH
Oversight of Extramural Research Inventions. Washington, DC: Department of Health
and Human Services.
U.S. Patent and Trademark Office. 2000. Performance and Accountability Report, Fiscal
Year 2000. Washington, DC: USPTO.
U.S. President's NIH Study Committee. 1965. Biomedical Science and Its Administration: A
Study of the National Institutes of Health. Report to the President. (Wooldridge Com-
mittee Report). Washington, DC: Government Printing Office.
Varmus H. 1998. New Directions in Biology and Medicine. Philadelphia, PA.
Varmus H. 1999. Evaluating the burden of disease and spending the research dollars of the
National Institutes of Health. N Engl J Med 340:1914-5.
Varmus H.2001. Public health. Proliferation of National Institutes of Health. Science 291~5510~:
1903-5.
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M,
Evans CA, Holt RA, Gocayne ID, Amanatides P. Ballew RM, Huson DH, Wortman JR,
Zhang Q. Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G. Thomas PD,
Zhang J. Gabor Miklos GL, Nelson C, Broder S. Clark AG, Nadeau J. McKusick VA,
Zinder N. Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R.
Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S. Kravitz
S. Levy S. Mobarry C, Reinert K, Remington K, Abu-Threideh J. Beasley E, Biddick K,
Bonazzi V, Brandon R. Cargill M, Chandramouliswaran I, Charlab R. Chaturvedi K,
Deng Z. Di Francesco V, Dunn P. Eilbeck K, Evangelista C, Gabrielian AK, Gan W. Ge
W. Gong F. Gu Z. Guan P. Heiman TJ, Higgins ME, Ji RR, Ke Z. Ketchum KA, Lai Z.
Lei Y. Li Z. Li J. Liang Y. Lin X, Lu F. Merkulov GV, Milshina N. Moore HM, Naik AK,
Narayan VA, Neelam B. Nusskern D, Rusch DB, Salzberg S. Shao W. Shue B. Sun J.
Wang Z. Wang A, Wang X, Wang J. Wei M, Wides R. Xiao C, Yan C, Yao A, Ye J. Zhan
M, Zhang W. Zhang H. Zhao Q. Zheng L, Zhong F. Zhong W. Zhu S. Zhao S. Gilbert
D, Baumhueter S. Spier G. Carter C, Cravchik A, Woodage T. Ali F. An H. Awe A,
Baldwin D, Baden H. Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A,
Cheng ML, Curry L, Danaher S. Davenport L, Desilets R. Dietz S. Dodson K, Doup L,
Ferriera S. Garg N. Gluecksmann A, Hart B. Haynes J. Haynes C, Heiner C, Hladun S.
Hostin D, Houck J. Howland T. Ibegwam C, Johnson J. Kalush F. Kline L, Koduru S.
Love A, Mann F. May D, McCawley S. McIntosh T. McMullen I, Moy M, Moy L,
Murphy B. Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H. Reardon M, Rodriguez
R. Rogers YH, Romblad D, Ruhfel B. Scott R. Sitter C, Smallwood M, Stewart E, Strong
R. Suh E, Thomas R. Tint NN, Tse S. Vech C, Wang G. Wetter J. Williams S. Williams
M, Windsor S. Winn-Deen E, Wolfe K, Zaveri J. Zaveri K, Abril JF, Guigo R. Campbell
MJ, Sjolander KV, Karlak B. Kejariwal A, Mi H. Lazareva B. Hatton T. Narechania A,
Diemer K, Muruganujan A, Guo N. Sato S. Bafna V, Istrail S. Lippert R. Schwartz R.
Walenz B. Yooseph S. Allen D, Basu A, Baxendale J. Thick L, Caminha M, Carnes-Stine
J. Caulk P. Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely
D, Esparham S. Fosler C, Gire H. Glanowski S. Glasser K, Glodek A, Gorokhov M,
Graham K, Gropman B. Harris M, Heil J. Henderson S. Hoover J. Jennings D, Jordan C,
Jordan J. Kasha J. Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J. Ma D,
Majoros W. McDaniel J. Murphy S. Newman M, Nguyen T. Nguyen N. Nodell M, Pan
S. Peck J. Peterson M, Rowe W. Sanders R. Scott J. Simpson M, Smith T. Sprague A,
Stockwell T. Turner R. Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A,
Zhu X. 2001. The sequence of the human genome. Science 291~5507~:1304-51.
Venter JC, Adams MD, Sutton GG, Kerlavage AR, Smith HO, Hunkapiller M. 1998. Shotgun
sequencing of the human genome. Science 280~5369~:1540-2.
Vogel G. 1999. A day in the life of a topflight lab. Science 285~5433~:1531-2.
OCR for page 211
REFERENCES
211
Wade N. 2001. Life Script: How the Human Genome Discoveries Will Transform Medicine
and Enhance Your Health. New York: Simon & Schuster.
Warner S. 2002. Once promising proteomics market sags. The Scientist 16~8~:18.
Washington Fax. 2001. DOE lab signs joint venture with Celera and Compaq to create
biology supercomputers. Washington, DC: Washington Fax.
Waterston RH, Lander ES, Sulston JE. 2002a. On the sequencing of the human genome. Proc
Natl Acad Sci USA 99:3712-6.
Waterston RH, Lindblad-Toh K, Birney E, Rogers J. Abril IF, Agarwal P. Agarwala R.
Ainscough R. Alexandersson M, An P. Antonarakis SE, Attwood J. Baertsch R. Bailey
J. Barlow K, Beck S. Berry E, Birren B. Bloom T. Bork P. Botcherby M, Bray N. Brent
MR, Brown DG, Brown SD, Butt C, Burton J. Butler J. Campbell RD, Carninci P. Cawley
S. Chiaromonte F. Chinwalla AT, Church DM, Clamp M, Clee C, Collins FS, Cook LL,
Copley RR, Coulson A, Couronne O. Cuff J. Curwen V, Cutts T. Daly M, David R.
Davies J. Delehaunty KD, Deri J. Dermitzakis ET, Dewey C, Dickens NJ, Diekhans M,
Dodge S. Dubchak I, Dunn DM, Eddy SR, Elnitski L, Emes RD, Eswara P. Eyras E,
Felsenfeld A, Fewell GA, Flicek P. Foley K, Frankel WN, Fulton LA, Fulton RS, Furey
TS, Gage D, Gibbs RA, Glusman G. Gnerre S. Goldman N. Goodstadt L, Grafham D,
Graves TA, Green ED, Gregory S. Guigo R. Guyer M, Hardison RC, Haussler D,
Hayashizaki Y. Hillier LW, Hinrichs A, Hlavina W. Holzer T. Hsu F. Hua A, Hubbard
T. Hunt A, Jackson I, Jaffe DB, Johnson LS, Jones M, Jones TA, Joy A, Kamal M,
Karlsson EK, Karolchik D, Kasprzyk A, Kawai J. Keibler E, Kells C, Kent WJ, Kirby A,
Kolbe DL, Korf I, Kucherlapati RS, Kulbokas EJ, Kulp D, Landers T. Leger JP, Leonard
S. Letunic I, Levine R. Li J. Li M, Lloyd C, Lucas S. Ma B. Maglott DR, Mardis ER,
Matthews L, Mauceli E, Mayer JH, McCarthy M, McCombie WR, McLaren S. McLay
K, McPherson JD, Meldrim J. Meredith B. Mesirov JP, Miller W. Miner TL, Mongin E,
Montgomery KT, Morgan M, Mott R. Mullikin JC, Muzny DM, Nash WE, Nelson JO,
Nhan MN, Nicol R. Ning Z. Nusbaum C, O'Connor MJ, Okazaki Y. Oliver K, Overton-
Larty E, Pachter L, Parra G. Pepin KH, Peterson J. Pevzner P. Plumb R. Pohl CS,
Poliakov A, Ponce TC, Ponting CP, Potter S. Quail M, Reymond A, Roe BA, Roskin
KM, Rubin EM, Rust AG, Santos R. Sapojnikov V, Schultz B. Schultz J. Schwartz MS,
Schwartz S. Scott C, Seaman S. Searle S. Sharpe T. Sheridan A, Shownkeen R. Sims S.
Singer JB, Slater G. Smit A, Smith DR, Spencer B. Stabenau A, Stange-Thomann N.
Sugnet C, Suyama M, Tesler G. Thompson J. Torrents D, Trevaskis E, Tromp J. Ucla C,
Ureta-Vidal A, Vins on JP, Von Niederhausern AC, Wade CM, Wall M, Web er RJ,
Weiss RB, Wendl MC, West AP, Wetterstrand K, Wheeler R. Whelan S. Wierzbowski J.
Willey D, Williams S. Wilson RK, Winter E, Worley KC, Wyman D, Yang S. Yang SP,
Zdobnov EM, Zody MC, Lander ES. 2002b. Initial sequencing and comparative analy-
sis of the mouse genome. Nature 420~6915~:520-62.
Wessely S. Wood F. 1999. Peer Review of Grant Applications: A Systematic Review. Peer
Review in Health Sciences. Annapolis Junction, MD: BMJ Publishing Group.
Yoshida M, Miyoshi I, Hinuma Y. 1982. Isolation and characterization of retrovirus from
cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl
Acad Sci USA 79:2031-5.
Zemlo TR, Garrison HH, Partridge NC, Ley TJ. 2000. The Physician Scientist: Career Issues
and Challenges at the Year 2000. Bethesda, MD: FASEB Life Sciences Forum. Pp. 14:221.
OCR for page 212
Representative terms from entire chapter:
genome project