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The RDA is defined as equal to the EAR plus twice the CV to cover the needs of 97 to 98 percent of individuals in the group (therefore, for molybdenum the RDA is 130 percent of the EAR). The calculated RDA is rounded to the nearest 1 μg.

RDA for Children

1–3 years

17 μg/day of molybdenum

4–8 years

22 μg/day of molybdenum

RDA for Boys

9–13 years

34 μg/day of molybdenum

14–18 years

43 μg/day of molybdenum

RDA for Girls

9–13 years

34 μg/day of molybdenum

14–18 years

43 μg/day of molybdenum

Adults Ages 19 Years and Older

Evidence Considered in Estimating the Average Requirement

The basis for an EAR for molybdenum was molybdenum balance in controlled studies with specific amounts of molybdenum consumed. Average balance achieved in four young men with an intake of 22 μg/day is shown in 6-day intervals in Figure 11-1 (Turnlund et al., 1995b). From day 1 to day 48, average balance was negative. Beginning at day 49, balance became slightly positive; through day 102, the average balance was positive in six of nine 6-day periods and negative in the other three 6-day periods. Over that entire period, average balance was near 0 (0.2 μg/day). Sixteen of the 36 individual 6-day balance periods were negative and 20 were positive. The average standard deviation of the nine 6-day balance periods was 2.6 μg/day with a range of 1.2 to 4.3 μg/day. The variability in balance for the 54-day balance period was 1.5 μg/day, or 7 percent of the dietary intake. The variability in the nine 6-day balance periods averaged 2.6 μg/day, or 12 percent.

The balance data suggest that 22 μg/day is near the minimum requirement. No clinical signs of deficiency were observed and biochemical changes associated with molybdenum deficiency were not found. Another group of four young men showed a similar balance pattern with negative balance during the first 6 days and becoming less negative over a 24-day period (Turnlund et al., 1995a). Twenty-



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