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Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
Hambidge (1976) and the high number of infants justifies a UF of 1.0, given that there is no evidence that intakes from formula of 5.8 mg/L of zinc result in infant toxicity.
Derivation of a UL. The NOAEL of 4.5 mg/day was divided by a UF of 1.0 to obtain a UL of 4 mg/day (rounded down) for infants ages 0 through 6 months. No adverse effects of zinc in children and adolescents could be found. Due to a dearth of information, the UL for young infants was adjusted for older infants, children, and adolescents on the basis of relative body weight as described in Chapter 2 and using reference weights from Chapter 1 (Table 1-1). Values have been rounded down.
Zinc UL Summary, Ages 0 through 18 Years
UL for Infants
4 mg/day of zinc
5 mg/day of zinc
UL for Children
7 mg/day of zinc
12 mg/day of zinc
23 mg/day of zinc
UL for Adolescents
34 mg/day of zinc
Pregnancy and Lactation
Because the UL is based on reduced copper status and because there are inadequate data to justify a different UL for pregnant and lactating women, the UL for pregnant and lactating women is the same as that for nonpregnant and nonlactating women.