Science

Products

Policies or Regulation

 

1854–1856

• Cigarette popularity grows between 1854 and 1856 during the Crimean War

 

1881

• James Bonsack of Virginia patents the first cigarette-making machine.

1893

• Pictet and Crepieux synthesize nicotine

 

1900

• Brosch appears to be the first investigator involved in experimental tobacco carcinogenesis. He applies tobacco (“juices”) to guinea pigs, observing epithelial proliferation

 

1913

• Camel brand is produced by R.J. Reynolds in 1913

 

1928

• Lombard and Doerring find an association between heavy smoking and buccal cancer

 

1938

• Pearl, a statistician and biometrician at Johns Hopkins, publishes the first statistical analysis comparing the health of smokers and nonsmokers and finds that individuals who smoked could expect shorter lives

1950

• Epidemiological studies report that lung cancer is particularly prevalent among cigarette smokers

1950

• Filters introduced

 



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement