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guest researcher at the NIMH and the INSERM in Creteil, France, served on a number of Advisory Committees for the NIH and Society for Neuroscience, won several research related awards, and is a member of editorial boards. Her research focuses on the development and plasticity of neocortex and the role of radial glia and Cajal Retzius cells in neuronal migration. She also studies the influence of neuronal migration on subsequent formation and processing within the cerebral cortex and the role of specific neurotrophins in neocortical plasticity.

Donald L. Price is Professor of Pathology, Neurology and Neuroscience and Director of the Division of Neuropathology at Johns Hopkins School of Medicine. Trained in neurology, neuropathology, and cell/molecular biology, Dr. Price's principle research interests are in the mechanisms of human neurodegenerative diseases, like Alzheimer's disease and amyotrophic lateral sclerosis (ALS). He and his collegues at Johns Hopkins have used transgenic strategies to introduce mutant genes into mice to reproduce the clinical, pathological, and biochemical phenotypes of AD, ALS, parkinsonism, and trinucleotide repeat expansion diseases in mice. These mice are being used to understand the pathogenic processes leading to these disorders. In addition, the Hopkins group has knocked out key genes/products relevant to these illnesses, work that has provided insights into therapeutic targets. Strategies effective in mice can be brought to clinical trials. He was elected to the Institute of Medicine in 1998, and is President-Elect of the Society for Neuroscience.

Raymond P. Roos is Professor and Chairman of the Department of Neurology at the University of Chicago. His main clinical interests are multiple sclerosis, CNS viral infections, and neurodegenerative disease. A basic goal of his studies is to use molecular techniques to better understand the pathogenesis of these diseases. He is interested in the pathogenesis of unconventional viral infections of the central nervous system, molecular determinants of neurovirulence and persistence of experimental viral infections in animals, and virus vectors in central nervous system gene delivery for use as neurobiological research tools and as a means for gene therapy.

Alan J. Thompson is Professor of Clinical Neurology and Neurorehabilitation in the Department of Clinical Neurology, Institute of Neurology, Queen Square, London, Medical Director of the NeuroRehabilitation Unit and Research and Development Director at the National Hospital for Neurology and Neurosurgery, Queen Square, London (affiliated with the University College of London). He is National Medical Advisor to the MS Society of Great Britain, President of ECTRIMS (European Committee for Treatment and Research in Multiple Sclerosis), European editor of the journal Multiple Sclerosis, and past-President of RIMS (Rehabilitation in Multiple Sclerosis). His main research interests are in the mechanisms underlying disability in neurological disorders, including mul-



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