Page 410

mother's immune system. It has been purified and used experimentally. No recommended use at present

Immunoglobulins (Gamma Globulin, Immunoglobulin G, IgG). Immunoglobulins are the antibody-containing fraction of human plasma. They are usually injected intramuscularly, but certain special preparations can be given intravenously. The evidence is conflicting as to whether intravenous IgG reduces the frequency of exacerbations in MS. Studies confirming that intravenous IgG might promote remyelination in humans have not been completed.

Immunobiological Revitalization. Purified rabbit antibodies against human bone marrow, spleen, and thymus, supplemented by an unidentified ”human placental product.“ This treatment is not recommended.

Proteolytic Enzymes. A mixture of digestive enzymes (pancreatin, chymotrypsin, and several others), given intravenously in repeated dosage. Inadequate published information exists to permit informed judgement about this therapy.

Chelation Therapy with Ethylenediamine Tetraacetic Acid (EDTA). A simple chemical that chelates metals very efficiently and is used in cases of lead poisoning to remove lead from the body. Must be injected intravenously over several hours. Chelation therapy for MS is not based on acceptable published evidence and is dangerous.

Physical and Surgical Manipulations

Acupuncture, Acupressure, Qigong. These procedures are part of traditional Chinese medicine (TCM). Acupuncture, a 4,000 year old Chinese procedure, is performed by inserting fine needles into specific skin sites with the expectation of influencing the function of underlying organs. The belief is that body energy flows in channels that connect to organs, and an imbalance can be restored by the acupuncture needles inserted into 365 points. Qigong is an approach to restore balance by deep breathing, concentration and relaxation exercises. This treatment is considered to have no effect on the disease process in MS and has not been shown to have any value in the symptomatic management of patients with disease.

Dorsal Column Stimulation. The dorsal columns of the spinal cord are large bundles of nerve fibers that carry the sense of touch and the sense of position from the legs, trunk, and arms up to the brain. The spinal cord is protected by a connective tissue wrapping known as dura. Electrical stimulation of the dorsal columns requires implantation of two electrodes on the overlying dura, which is done by passing the electrodes

The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement