TABLE 6-1 Epidemiologic Studies—Occupational Exposure

Reference

Study

Design Description

Study Group (N)

Comparison Group (N)a

Production Workers

New NIOSH Studies

Calvert et al., 1999

Cohort

Continuing follow-up of workers employed more than 15 years ago at two plants that manufactured substances contaminated with TCDD to evaluate associations between serum TCDD and serum glucose (diabetes), TSH, total T4, and T3

281

260

Steenland et al., 1999

Cohort

Mortality study of workers at 12 industrial plants that produced chemicals contaminated with TCDD, using a job-exposure matrix to estimate TCDD exposure categories. End points reported are all cancers, ischemic heart disease, and diabetes

5,132 (3,538 with exposure data divided into septiles of cumulative exposure; 608 who had chloracne)

Calvert et al., 1998

Cohort

Continuing follow-up of workers employed more than 15 years ago at two plants that manufactured substances contaminated with TCDD to evaluate the association between TCDD exposure and cardiovascular outcomes

281

260



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