TABLE 6-2 Epidemiologic Studies—Environmental Exposure

Reference

Study Design

Description

Study Group (N)

Comparison Group (N)a

New Studies from Seveso

Bertazzi et al., 2001

Cohort

Mortality (through 1996) study of residents in industrial accident exposure-related geographic regions

804 zone A

5,941 zone B

38,624 zone R

232,745

Bertazzi et al., 1998;

Pesatori et al., 1998

Cohort

Mortality (through 1991) study of residents in industrial accident exposure-related geographic regions

805 zone A

51,943 zone B

38,625 zone R

232,747

Seveso Studies Reviewed in Update 1998

Bertazzi et al., 1997

Cohort

Study of cancer incidence among Seveso residents in contaminated zones (A, B, R) after 15 years of follow-up through 1991

45,373 total

805 zone A

5,943 zone B

38,625 zone R

232,747

Mocarelli et al., 1996

Cohort

Study of sex ratio among the offspring of Seveso residents born in zone A from (1) 1977 to 1984 and (2) 1985 to 1994

(1) 74 births (28 male, 48 female)

(2) 124 births (60 male, 48 female)

 

Seveso Studies Reviewed in Update 1996

Bertazzi et al., 1993

Cohort

Study of cancer incidence in Seveso residents (aged 20 to 74 years) in contaminated zones (A, B, R) exposed to TCDD on July 10, 1976, compared to neighboring residents in unexposed areas

724 zone A

4,824 zone B

31,647 zone R

181,579



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