somatic cell nuclear transfer technique (SCNT), 5, 10, 11, 12, 37, 39, 45, 46, 47, 59

Embryos, 14

animal models, 21, 23, 27, 33, 41

defined, 68

ectoderm, 13, 21

morulas, 13, 70-71

zygotes, 13, 14, 15, 37, 72

Endoderm, 13, 21

defined, 69

Ethical issues, see Philosophical, ethical and legal issues

Eyes, 16

adult stem cells, 23, 25-26, 28

committee biographies, 82

committee workshop agenda, 80

F

Fats, see Adipocytes;

Lipids

Feeder cells, 33, 36

Fertilization, 14, 15

cloning, 11, 47

defined, 69

in vitro, 43, 48, 70

morula, 70-71

zygotes

Fetal stem cells, 14, 16, 29

cloning vs, 11, 47

defined, 13-14

Food and Drug Administration, 54, 80, 86

France, 46

Funding, 48-54, 57-58

embryonic stem cells, 3-4, 5, 35, 49-51, 58, 59

private sector, 3, 49-52, 57

report at hand, xi, 9

research, general, 3-4, 51-52

G

Genetic disorders, 8, 17, 84

adult stem cells, 24

Germany, 46

Germ cells, 16

defined, 69

Gonadal ridge, 16

defined, 69

germ cells, 16, 69

Graft-versus-host disease, 21-22

defined, 69

H

Hematopoietic stem cells (HSCs), 56

adult, 16, 19-23, 25, 26, 29, 47

animal models, 21, 23, 25, 29

defined, 69

differentiation, 19, 20

embryonic, 32, 33, 34, 35, 47

fetal, hepatic system, 13, 16, 29, 80

T cells, 20, 21

Hepatic system, 7

adult stem cells, 23, 26

committee workshop agenda, 79-80

defined, 69

embryonic stem cells, 34, 38

fetal hematopoietic stem cells, 13, 16, 29, 80

Histocompatibility, 4, 21

adult stem cells, 21-22, 24, 26

autologous transplants, 24, 27, 67

committee recommendations, 5

defined, 69

embryonic stem cells, 34-35, 36, 38-39, 47

graft-versus-host disease, 21-22, 69

immunosuppressive drugs, 4, 34

transplant rejection, 4, 10, 12, 21-22, 24, 34-35, 36, 38-39, 47, 58

I

Immune system

see also Histocompatibility

adult stem cells, 19, 21-22, 24, 26

antigens, 67, 71

surface antigen, 22-23, 38, 71, 72

autologous transplants, 24, 27, 67



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement