TABLE 1 Rates of Success/Failure of Somatic Cell Nuclear Transfer in Mammals

1

2

3

4

5

6

Speciesa

Cell typeb

# Embryos producedc

# Embryos developed into morula/ blastocyst (%)d

# Fetuses after embryo transfere

# Fetuses miscarried (%)f

Sheep

Embryo-derived epithelial-like

244

34 (14)

8

3 (38)

Adult mammary gland

277

29 (12)

1

0 (0)

Fetal fibroblast

172

47 (27)

5

2 (40)

Embryo-derived epithelial-like

385

126 (33)

15

11 (73)

Fetal fibroblast

507

69 (13.6)

14

7 (50)

ES cell line-derived epithelial-like

128

31 (24.2)

>9

>7 (~78)

ES cell line-derived epithelial-like

258

44 (17)

>11

>10 (~91)

ES cell line-derived epithelial-like

423

75 (18)

8

5 (63)

ES cell line-derived fibroblast-like

158

39 (31)

10

7 (70)

ES cell line-derived fibroblast-like

187

51 (27)

15

8 (53)

Fetal fibroblast

417

80 (19)

20

6 (30)

Cattle

Blastomere (embryonic)

641

152 (24)

>13

>4 (~31)

Blastomere (embryonic)

132

84 (64)

N/A

N/A

Embryonic stem cell

239

42 (18)

N/A

N/A

Fetal fibroblast

276

33 (12)

6

2 (33)

Adult mural granulosa from 13 yr old cow

621

259 (42)

28

26 (93)



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