Questions? Call 888-624-8373

PAPERBACK + PDF
your price: $41.00
add to cart

PAPERBACK
list:$35.00
Web:$31.50
add to cart

PDF BOOK
your price: $27.00
add to cart

PDF CHAPTERS
your price: $3.40
select

Rights & Permissions

topleft topright

Scientific and Medical Aspects of Human Reproductive Cloning (2002)
Committee on Science, Engineering, and Public Policy (COSEPUP)
Board on Life Sciences (BLS)

Page
136
bottomleft bottomright

The following HTML text is provided to enhance online readability. Many aspects of typography translate only awkwardly to HTML. Please use the page image as the authoritative form to ensure accuracy.


Scientific and Medical of Aspects: Human Reproductive Cloning

TABLE 3 Developmental Capacity of Cytoplasts Reconstituted with Nuclei from Embryonic Cells

1

2

3

4

5

Species

Recipient cytoplast

Donor cell type

% Early Development: % Blastocyst (# Blastocysts/ # Cultured)

% Term Development: % Offspring (# Live births/ # Transferred)

Mouse

Zygote

Inner cell mass

16% (23/142)

19% (3/16)

Trophectoderm

1% (1/68)

0

Zygote

Pronuclear

95% (20/21)

no transfer

2-cell

13% (19/151)

no transfer

4-cell

0 (0/81)

no transfer

8-cell

0 (0/111)

no transfer

Inner cell mass

0 (0/84)

no transfer

Zygote

8-cell

0(0/32)

no transfer

Inner cell mass

0 (0/84)

no transfer

Zygote

8-cell

0(0/32)

no transfer

2-cell blastomere

2-cell

93% (40/43)

24%a (10/41)

Zygote

8-cell

51% (45/89)

0a (0/11)

Cumulus cell

0 (0/91)

no transfer

2-cell blastomere

4-cell

72% (49/68)

22% (10/46)

8-cell

35% (49/139)

8% (4/48)

Inner cell mass

0 (0/91)

no transfer

Mll oocyte

2-cell

23% (20/88)

15% (3/20)

8-cell

4% (1/26)

0 (0/1)

Inner cell mass

13% (11/87)

0 (0/11)

2-cell

78% (36/46)

29% (10/34)

4-cell

71% (30/42)

22% (6/27)

8-cell

46% (18/39)

18% (3/17)

4-cellc

83% (58/70)

43% (2/58)

Inner cell massc

64% (23/36)

11% (2/18)

Trophectodermc

62% (16/26)

8% (2/25)

ES cell

5% (47/931)

0 (0/56)

ES cell

29% (312/1087)

6% (8/132)

Sheep

Mll oocyte

8-cell

33% (8/24)

75% (3/4)

 

16-cell

27% (13/49)

21% (3/14)

Page
136