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Immunization Safety Review: Multiple Immunizations and Immune Dysfunction (2002)
Institute of Medicine (IOM)

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. "Appendix A: Chronology of Important Events Regarding Vaccine Safety." Immunization Safety Review: Multiple Immunizations and Immune Dysfunction. Washington, DC: The National Academies Press, 2002.

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Immunization Safety Review: Multiple Immunizations and Immune Dysfunction

Year

Vaccine Licensure

Legislation and/or Policy Statements

IOM Reports on Vaccine Safety

1985

Hib vaccine licensed for children >15 months

 

1986

 

Congress passes Public Law 99–660, the National Childhood Vaccine Injury Act (introduced in 1984) calls for:

• est. of NVPO

• est. of NVAC

• est. of VICP

• est. of ACCV

IOM review of 1) pertussis and rubella, 2) routine child vaccines

 

1988

 

Evaluation of Poliomyelitis Vaccine Policy Options

1990

2 Hib conjugate vaccines licensed for use beginning at 2 months

 

1991

Acellular pertussis component licensed for the 4th and 5th doses of the 5-part DTP series in ACELIMUNE

Hepatitis B recommended by ACIP for addition to childhood immunization schedule

ACIP recommends Hib be added to childhood immunization schedule

Adverse Effects of Pertussis and Rubella Vaccines

1992

Acellular pertussis component licensed for the 4th and 5th doses of the 5-part DTP series in Tripedia

Hepatitis B vaccine: Added universal vaccination for all infants, high-risk adolescents (e.g., IV drug users, persons with multiple sex partners)

 

1993

Combined DTP and Hib vaccine (Tetramune) licensed

 

1994

 

Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality

DPT and Chronic Nervous System Dysfunction: A New Analysis

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