tussis vaccines. Studies of the efficacy of Streptococcus pneumoniae vaccines are in progress. Her laboratory efforts have focused on the standardization of serologic markers of vaccine response and correlates of protection against natural disease. Dr. Edwards is a member of the Society for Pediatric Research and is a fellow of the Infectious Diseases Society of America and the American Academy of Pediatrics. She has previously served as a member of the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention and the Vaccines and Related Biological Products Advisory Committee of the Food and Drug Administration.

Denise L. Faustman, M.D, Ph.D., is an associate professor of medicine at Harvard Medical School and director of immunobiology at the Massachusetts General Hospital. Her research interests include diabetes, autoimmune diseases, and transplantation. Many of her experimental approaches capture the molecular and genetic bases of preferential autoimmune disease expression in women. She was the inventor of the concept of modifying donor antigens on cells before transplantation, which serves as the platform technology for the use of cloning technology in this clinical arena. Over the past 10 years she discovered two deranged biological pathways in autoimmune lymphocytes that now serve as potential therapeutic sites for the permanent reversal of autoimmunity. In the case of murine autoimmune models, the complete reversal of established diabetic autoimmunity has yielded the first data demonstrating the regeneration in situ of the missing islet tissue. She serves as co-editor-in-chief of the Journal of Women’s Health and Gender-Based Medicine and since 2000 has served as chairman of the board for the Society for the Advancement of Women’s Health Research. She has served on several National Research Council and Institute of Medicine committees, including the Committee on Methods for Producing Monoclonal Antibodies, Committee for Xenograft Transplantation, and the Committee on Gender Differences in Susceptibility to Environmental Factors.

Emil C. Gotschlich, M.D., is vice president for medical sciences at the Rockefeller University, where he is also R. Gwin Follis-Chevron Professor and head of the Laboratory of Bacterial Pathogenesis and Immunology. His early work led to the development of a vaccine for the prevention of group A and C meningococcal meningitis. His research has also been directed at the surface structures responsible for the pathogenicity of group B streptococci and gonococcus. Dr. Gotschlich is a fellow of the American Academy of Microbiology and is a member of both the National Academy of Sciences and the Institute of Medicine.

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