INDICATIONS AND USAGE

Immunization with Anthrax Vaccine Adsorbed is recommended for individuals who may come in contact with animal products such as hides, hair, or bones which come from anthrax endemic areas and may be contaminated with Bacillus anthracis spores; and for individuals engaged in diagnostic or investigational activities which may bring them into contact with B. anthracis spores (1,5). It is also recommended for high risk persons such as veterinarians and others handling potentially infected animals. Since the risk of exposure to anthrax infection in the general population is slight, routine immunization is not recommended.

If a person has not previously been immunized against anthrax, injection of this product following exposure to anthrax bacilli will not protect against infection.

CONTRAINDICATIONS

A history of a severe reaction to a previous dose of anthrax vaccine is a contraindication to immunization with this vaccine.

WARNINGS
  1. Any acute respiratory disease or other active infection is generally considered to be adequate reason for deferring an injection.

  2. Persons receiving cortico-steroid therapy or other agents which would tend to depress the immune response may not be adequately immunized with the dosage schedule recommended. If the therapy is short termed, immunization should be delayed. If the therapy is long termed, an extra dose of vaccine should be given a month or more after therapy is discontinued.

PRECAUTIONS
  1. General: Epinephrine solution, 1:1000, should always be available for immediate use in case an anaphylactic reaction should occur, even though such reactions are rare.

  2. Carcinogenesis, Mutagenesis, Impairment of Fertility: Studies have not been performed to ascertain whether Anthrax Vaccine Adsorbed has carcinogenic action, or any effect on fertility.

  3. Pregnancy: PREGNANCY CATEGORY C. ANTHRAX VACCINE ADSORBED Animal reproduction studies have not been conducted with Anthrax Vaccine Adsorbed. It is also not known whether Anthrax Vaccine Adsorbed can cause fetal harm when administered to a pregnant woman or



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement