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Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products (2002)

Chapter: Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda

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Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
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Appendix C
2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products

AGENDA

The National Academies

2101 Constitution Avenue, NW

Washington, D.C. 20418

MONDAY, November 5, 2001

8:00 a.m.

Breakfast

8:30 a.m.

Introductions and welcome —Nancy Targett, Committee Chair, University of Delaware, Jennifer Merrill, Study Director, Ocean Studies Board

SESSION 1: DRUG DISCOVERY AND DEVELOPMENT

8:45 a.m.

Session chairs—Shirley Pomponi, Harbor Branch Oceanographic Institute, William Gerwick, Oregon State University

8:55 a.m.

Accessing new materials: Supply issues, uncultured species—William Fenical, Scripps Institution of Oceanography

Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×

9:25 a.m.

Discussion

9:35 a.m.

Novel screening directions and technologies: Analytical techniques, retrospective views, development bottlenecks—Guy Carter, Wyeth Ayerst

10:05 a.m.

Discussion

10:15 a.m.

Break

10:30 a.m.

The oceans: A rich source of drugs to treat human disease—Mary Ann Jordan, University of California, Santa Barbara

11:00 a.m.

Discussion

11:10 a.m.

Ecological roles: Mechanisms for discovery of novel targets, comparative biochemistry—Patrick Walsh, Rosenstiel School of Marine and Atmospheric Science

11:40 a.m.

Discussion

11:50 a.m.

Molecular biology and natural products—Bradley Moore, University of Arizona

12:20 p.m.

Discussion

12:30 p.m.

Lunch

SESSION 2: GENOMIC AND PROTEOMIC APPLICATIONS FOR MARINE BIOPRODUCT DISCOVERY

1:30 p.m.

Session chairs—D. Jay Grimes, University of Southern Mississippi, John Heidelberg, The Institute for Genomic Research

1:40 p.m.

The genomics revolution: Challenges and opportunities— Claire Fraser, The Institute for Genomic Research

Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×

2:10 p.m.

Discussion

2:20 p.m.

Bringing culture to the uncultured: Microbial discovery by high throughput cultivation—Stephen Giovannoni, Oregon State University

2:50 p.m.

Discussion

3:00 p.m.

Microbial microarrays: Utility, limitations and future applications, lessons learned from several model systems—Scott Peterson, The Institute for Genomic Research

3:30 p.m.

Discussion

3:40 p.m.

Break

4:00 p.m.

Microbial genomics: Where do we go now?—Daniel Drell, U.S. Department of Energy

4:30 p.m.

Discussion

4:40 p.m.

Summary discussion of events, led by Nancy Targett

5:15 p.m.

Reception – Rotunda

6:00 p.m.

Evening lecture—Marine biotechnology, past, present and future—Rita R. Colwell, National Science Foundation

6:45 p.m.

Discussion

7:30 p.m.

Workshop adjourns for the day

TUESDAY, November 6, 2001

8:00 a.m.

Breakfast

8:30 a.m.

Introductions—Dr. Nancy Targett, University of Delaware

Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×

SESSION 3: BIOMATERIALS AND BIOENGINEERING

8:45 a.m.

Session chairs—Roger Prince, ExxonMobil Research, Robert Baier, SUNY Buffalo

8:55 a.m.

Bioadhesives: Biocatalysis, post translational modification—Christine Benedict, Geneva Pharmaceuticals, Inc.

9:25 a.m.

Discussion

9:35 a.m.

Self-cleaning surfaces: Biolubricants, drag reduction— Anne Meyer, State University of New York at Buffalo

10:05 a.m.

Discussion

10:15 a.m.

Break

10:30 a.m.

Uniform microporous biomaterials prepared from marine skeletal precursors—Rodney White, UCLA Medical Center

11:00 a.m.

Discussion

11:10 a.m.

Polymers for tissue engineering: Drug delivery and cellular therapy—Cato Laurencin, Drexel University

11:40 p.m.

Discussion

12:00 p.m.

Lunch

SESSION 4: PUBLIC POLICY, PARTNERSHIPS, AND OUTREACH

12:50 p.m.

Session chairs—Nancy Targett, Committee Chair, University of Delaware, Jennifer Merrill, Ocean Studies Board

Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×

1:00 p.m.

Biomedical compounds extracted from coral reef organisms: Harvest pressure, conservation concerns, and sustainable management—Andrew Bruckner, NOAA Office of Protected Resources

1:30 p.m.

Discussion

1:40 p.m.

Productive partnerships in natural products discovery and development—Joshua Rosenthal, Fogarty Center (NIH)

2:10 p.m.

Discussion

2:20 p.m.

Break

2:30 p.m.

Commercialization of marine bioproducts: Intellectual property and technology transfer issues—Donald Gerhart, University of Oregon

3:00 p.m.

Discussion

3:10 p.m.

Planning, partnerships, and progress in marine biotechnology research and outreach in Florida—James Cato, University of Florida Sea Grant Program

3:40 p.m.

Discussion

3:50 p.m.

Workshop wrap-up

Session chairs present 10-minute summaries of the topics discussed

4:30 p.m.

Final discussion of the topic

5:30 p.m.

Workshop adjourns

Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×
Page 109
Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×
Page 110
Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×
Page 111
Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×
Page 112
Suggested Citation:"Appendix C: 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products - Agenda." National Research Council. 2002. Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products. Washington, DC: The National Academies Press. doi: 10.17226/10340.
×
Page 113
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Dramatic developments in understanding the fundamental underpinnings of life have provided exciting opportunities to make marine bioproducts an important part of the U.S. economy. Several marine based pharmaceuticals are under active commercial development, ecosystem health is high on the public's list of concerns, and aquaculture is providing an ever greater proportion of the seafood on our tables. Nevertheless, marine biotechnology has not yet caught the public's, or investor's, attention. Two workshops, held in October 1999 and November 2001 at the National Academies, were successful in highlighting new developments and opportunities in environmental and biomedical applications of marine biotechnology, and also in identifying factors that are impeding commercial exploitation of these products. This report includes a synthesis of the 2001 sessions addressing drug discovery and development, applications of genomics and proteomics to marine biotechnology, biomaterials and bioengineering, and public policy and essays contributed by the workshop speakers.

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