. "Appendix A: Committee Conclusions and Recommendations from Previous Reports." Immunization Safety Review: Hepatitis B Vaccine and Demyelinating Neurological Disorders. Washington, DC: The National Academies Press, 2002.
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Immunization Safety Review: Hepatitis B Vaccine and Demyelinating Neurological Disorders
Public Health Response Recommendations
The committee recommends that state and federal vaccine policymakers consider a broader and more explicit strategy for developing recommendations for the use of vaccines.
The committee does not recommend a policy review—by the CDC’s Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics’ Committee on Infectious Diseases, and the American Academy of Family Physicians—of the current recommended childhood immunization schedule on the basis of concerns about immune system dysfunction.
The committee does not recommend a policy review by the Food and Drug Administration’s Vaccines and Related Biologic Products Advisory Committee of any currently licensed vaccines on the basis of concerns about immune system dysfunction.
The committee recommends exploring the feasibility of using existing vaccine surveillance systems, alone or in combination, to study safety questions related to asthma and other important allergic disorders, as well as to type 1 diabetes and other important autoimmune diseases.
The committee recommends exploring the use of cohorts for research on possible vaccine-related disease risks. Furthermore, the committee recommends that disease registries and research programs for autoimmune and allergic disorders routinely collect immunization histories as part of their study protocol.
Basic Science and Clinical Research
The committee recommends continued research on the development of the human infant immune system.
The committee endorses current research efforts aimed at identifying genetic variability in human immune system development and immune system