Benn J, Schneider RJ. 1994. Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade. Proceedings of the National Academy of Sciences 91:10350–10354.

Bennett WP, Hollstein MC, Metcalf RA, Welsh JA, He A, Zhu S, Kusters I, Resau JH, Trump BF, Lane DP, Harris CC. 1992. p53 mutation and protein accumulation during multistage human esophageal carcinogenesis. Cancer Research 52:6092–6097.

Bird A. 1992. The essentials of DNA methylation. Cell 70:5–8.

Bohlke K, Cramer DW, Trichopoulos D, Mantzoros CS. 1998. Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast. Epidemiology 9(5):570–573.

Bohr VA, Anson RM. 1995. DNA damage, mutation and fine structure DNA repair in aging. Mutational Research 338:25–34.

Brash DE, Rudolpht JA, Simon JA, Lin A, McKenna GJ, Badent HP, Halperin AI, Ponten J. 1991. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proceedings of the National Academy of Sciences 88:10124–10128.

Burbee D, Forgacs E, Zöchbauer-Müller S, Shivakuma L, Fong K, Gao B, Randle D, Virmani A, Bader S, Sekido Y, Latif F, Milchgrub S, Gazdar A, Lerman M, Zabarovsky E, White M, Minna J. 2001. RASSF1A in the 3p21.3 homozygous deletion region: Epigenetic inactivation in lung and breast cancer and suppression of the malignant phenotype. Journal of the National Cancer Institute 93:(in press).

Byrne C, Colditz G, Willett F, Speizer F, Pollak M, Hankinson S. 2000. Plasma insulin-like growth factor (IGF) I, IGF-binding protein-3, and mammographic density. Cancer Research 60(14): 3744–3748.

Caselmann WH, Meyer M, Kekule AS, Lauer U, Hofschneider PH, Koshy R, 1990. A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA. Proceedings of the National Academy of Sciences 87:2970–2974.

Cedar H. 1988. DNA methylation and gene activity. Cell 53:3–4.

Chen J, Giovannucci E, Kelsey K, Rimm EB, Stampfer MJ, Colditz GA, Spiegelman D, Willett WC, Hunter DJ. 1996. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer Research 56:4862–4864.

Chen J, Giovannucci E, Hankinson SE, Ma J, Willett WC, Spiegelman D, Kelsy KT, Hunter DJ. 1998. A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphims, and risk of colorectal adenoma. Carcinogenesis 19:2129–2132.

Clarke RB, Howell A, Anderson E. 1997. Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone. British Journal of Cancer 75:251–257.

Coffey DS. 1993. Prostate cancer. An overview of an increasing dilemma. Cancer 71(3):880–886.

Coffey DS. 2001. Similarities of prostate and breast cancer: Evolution, diet and estrogens. Urology 57(4A):31–38.


Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. 2000. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nature Genetics 25:315–319.

Davidoff AM, Humphrey PA, Iglehar ID, Marks JR. 1991. Genetic basis for p53 overexpression in human breast cancer. Proceedings of the National Academy of Sciences 88:5006–5010.

Davidow AL, Neugut AI, Jacobson JS, Habibul A, Garbowski GC, Forde KA, Treat MR, Waye JD. 1996. Recurrent adenomatous polyps and body mass index. Cancer Epidemiology, Biomarkers, and Prevention 5:313–315.

Dianov GL, Timchencko TV, Sinitsina OI, Kuzminov AV, Medvedev OA, Salganik RI. 1991. Repair of uracil residues closely spaced on opposite strands of plasmid DNA results in doublestrand break and deletion formation. Molecular Genetics and Genomics 225:448–452.

Dong C, Hemminki K. 2001. Multiple primary cancers at colon, breast and skin (melanoma) as models for polygenic cancers. International Journal of Cancer (in press).



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