. "6. Special Address: A Novel Approach to Cancer Treatment Based on Immune Stimulations and Other Environmental Approaches." Cancer and the Environment: Gene-Environment Interactions. Washington, DC: The National Academies Press, 2002.
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Cancer and the Environment: Gene-Enviroment Interaction
types of MNC molecules. Individual patients can react against multiple antigens. It is the cellular arm of the immune response that is predominantly involved in immune reactivities, and a key question is whether we can use this information to generate antitumor T cells by immunizing patients using a vaccine.
In a pilot trial, we demonstrated that a modified peptide could consistently immunize cancer patients and generate T cells in their circulation that can recognize the cancer. Work by us and others has opened new possibilities for the development of effective immunotherapies for the treatment of cancer.