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IlPE~METHbIM YKA3ATE~b A ABapunHme cuTyaunn 19 - 21, 5 1, 6 8 ABToK~aB~poBaHHe KOpMa ~ HO~CT~a 42-44, 46 ,=H x~pypr~ecKHx rIpoLle'~yp 68, 86 A,z~ariTau~ 63-64 AKK~HMaTH3a~ ~ a~anTau He,~aBHO rIpHo6peTeHHux ~BOTHuX 63, 64 ~BOTHuX, co,~ep~a~nxcH Ha OTKpuTOM Bo3~yxe 27, 33, 34 AKTHBHOCTB ~ MOUnOH 42 A ~B6nHH3M 3 8 - 3 9 A~BTepHaTHBM ncc~e'~oBaH~M Ha ~BOTHuX 1, 1 l, 124 peKoMeH~yeMa~ ~nTepaTypa 89 AMep~KaHcKaH Alcoa 3a ryMaHHoe oTHomeHHe (AMA) 1 10 AMep~KaHcKaH acco~Ha~ rIo aKKpe,~nTOBaHHIO BuBapHeB (AAALAC) 108 AMep~KaHcKaH acco~Ha~ rIo HayKe O ~a6opaTopHux ~BOTHuX (AALAS) 15, 108-109 AMep~KaHcKaH BeTep~HapHaH acco~Ha~ (AVMA) 72, 111 AMep~KaHCKaSI Ko~er~ r~o Me~HHCKOMy obecne~eHn~o ~abopaTopHux ~BOTHuX (ACLAM) 109 AMep~KaHCKOe 06~eCTBO nH*eHepOB rIo Te~OBuM, XO~O,~BHuM BO3,~y~HuM KOH~HOHHuM yCTaHOBKaM (ASHRAE) 35 AMep~KaHcKoe o6~ecTBo HpaBcTBeHHoro BocrInTaH~ (AMES) 117 AMep~KaHcKoe o6~ecTBo rIpuMaTO~OrOB (ASP) 1 10- 1 1 1 AMep~KaHcKoe o6~ecTBo pa6oTalo~nx C ~a6opaTopHuMn ~BOTHuMn (ASLAP) 110 AMrlyTa~ rIa~B~eB 51 AHa~re3~ ~ aHa~reT~Ku 14, 70-72 peKoMeH,~yeMa~ JI~TepaTypa 90-91 AHecTe3~ ~ aHecTeT~Ku 14, 70-72 peKoMeH,~yeMa~ JI~TepaTypa 90-91 B~XO,~ H3 HapKo3a 7O, 8 6 - 8 7 oTpa6oTaHHMe ra3M 19 AHKCHO~HT~KH 7 1 AHTH6~0T~KH 67 Acco~Ha~ BeTep~HapoB-rIpuMaTo~oroB (APV) 1 12 Acco~Ha~ rIo co'~ep~aHHIo ~a6opaTopHux ~BOTHuX (LAMA) 1 16-1 17 AyT6p~nHr 52-53 b Bap~epHme Bxo~Hme c~cTeMm 18 BercTBo 25-26 ~e3orIacHocTE CM. tHrneHa Tpy,~a ~ 6e3orIacHocTE rIepcoHaJIa ~6JIHOTeKa pernoHaJI~Horo rIpuMaToJIor~ecKoro Hay'IHO- nccJIe'~oBaTeJIBcKoro LleHTpa IIITaTa BUCKOHCHH (VVRPRC) 120 126

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v I7PE#METHLIB ~A3ATE~L Bno~or~ecKne areHTu ~ onacHocT~ 16, 18-19, 49 peKoMeH~yeMa~ ~nTepaTypa 92-93 HKB~a~ OTXO~OB 49-50 ~HO~Or~eCKH 6e30HaCHMe 60KCM 18-19, 83 Bomb 7O, 124 KOHTpOJIB2, 11, 14, 70-72, 124 anTaHa3~ 11, 72-73 Bu3BaHHa~ ripoue~ypaMn 1 1- 13, 72, 124 peKoMeH,~yeMa~ JI~TepaTypa 90-91 Topeka C Bpe~HTe~MU 50-51 B BaKunHau~ nepcoHa~a ~abopaTopun 20 BeHTlIJDq~ ~ B03~HMU HOTOK 19, 24-27, 32, 34-38, 83-85 BeTep~HapHaSI HOMONYM 13, 14, 61-73, 124 BeTep~Hapu, y~acTne ~ KoHcy~BTaunn 14 oTBeTcTBeHHocTB9-11, 14, 51, 63-7O, 124 B~H~OBMU H0~ 26 BTIPYC rerIaTHTa MMIIIeH 65-66 B~pyc HMMyHO~e~HTa 06e3B~H 64 B~pyc ~HM~O~HTapHOrO XOpHOMeHUHrUTa 66 B~pyc cna~o~aKpnoa~eHuTa 65 BuTaM~H C 43-44 B~a*HocT~ ~ B~ara 24-25, 32, 34, 37, 82 Bo~a, o6ecHeHeHHe 44-45 HO~KH 28, 45, 48 orpaH~eHne rioTpe6~eH~ 13-14 BO3,~Y~HMU rIOTOK CM. BeHT~q~ ~ BO3,~y~HMn rIOTOK BocrIpHuMHuBocTB K 3a6o~eBaH~M 25, 41 BTop~HMe orpa;K,D;eH~ 24, 32, 49 ~sepu ~ oKHa 79-80 BeHT~HLl~ ~ BO3,~yIIIHMn rIOTOK 24, 34-38 CM. TaK*e K~eTKH ~ pa3Me~eHHe B HuX BuroHm ~ rIacT6~ma 5, 26, 27, 42 BucoTa orpa;K,D;eHHn 29-31 B~xo'~HMe ,~Hn, yXo'~ 3a ~BOTHuMn 51 FeMoppar~ecKa~ ~nxopa~Ka obe3~H 64 FeHeT~Ka 52-53 peKoMeH~yeMa~ JInTepaTypa 98-99 FurneHa Tpy~a ~ 6e3orIacHocT~ rIepcoHaJIa 7, 11, 16-20 peKoMeH~yeMa~ JInTepaTypa 92-93 Fo~y6n 3 1 tpyrIrIM CM. coLlHaJILHMe rpyrIrIM ~ coLlHaJILHoe B3aHMo'~encTBue Epu3yHm 4O, 44, 48, 63 a~B6nHH3M ~ ~OTOTOKC~HOCTB 39 3a60JIesaH~ 64-65 Tpe6oBaH~ K pa3Me~eHHIo 26-3O, 34 nH6p~nHr 53 127

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128 CBO60~HMe OT HaTOreHH~X M~KpOOpraHH3MOB 66 peKoMeH~yeMa~ JInTepaTypa 103-105 x~pypr~ecKne rIpoL~e~ypu 69, 85 aM~yTau~ rates 53 EyMaHuTapHoe 06mecTso Coe~nHeHHux IIITaTos (HSUS) 115 ,~asJIeHne so3~yxa 18-19, 34, 83, 86 ,~sepu 79-80 ,~syxKop~opHme c~cTeMm 18-19 ,~er~paTaL~ 13 ,~e3nH~eKL~ 25, 26, 46-49 '~epes~HHme MaTepua~m 25-26, 46 ,~e~eKaL~ 25, 47 ,~narHo3 65-66 ~HKHe BOTHER CM. 3K30T~eCKHe ~ ~HKHe BOTHER '~ncTpecc ~ 3nTaHa3~ 11, 72, 73 su3usaeMun r~poue~ypaMn 1 1-12, 72, 124 ,~OMa~H~uq retina 34 Spat ~BOTH~X 41 ~peHa*HMe CTOKH 1 9, 27, 8 1 ~peCCHpOBKa ~BOTH~X 1 1 - 12, 26-27 ,~yIII 17, 19, 79 E EcTecTseHH~Ie ycJIos~ ape 2, 4, 5, 24, 27 An soothe c oc~a6~eHH~IM nMMyHuTeToM 16, 24, 49 3 3aroHEI 25-27,42,47-49 3aKoH of ncHe3aI0r~nx Borax 122 3aKoH O 3a~nTe ~BOTHEIX 121 3aKpe~eHHe B Specie 12 3aKyrIKa ~BOTHEIX 62 Banal 35-38,47-49 3amuTa OpraHOB ~BIXaH~ 19 3a~nTa c~yxa 19 3ar~nTHaH ova 15- 16,18- 19 3eMHOBO~HEIe, peKOMeH~yeMaH ~nTepaTypa 90 300H03BI 7,16-2O,64 peKoMeH~yeMa~ ~nTepaTypa 92-93 3oonapKos~Ie soothe, peKoMeH~yeMa~ ~nTepaTypa 96-97 300TexH~K~, oGy~eHne ~ no~roTosKa 14 peKoMeH~yeMa~ ~nTepaTypa 106-107 tI~~eHTH~nKa~ ~BOTHEIX 51,65 II30~q~ CM. KapaHTHH; pa3~e~EHoe co,~ep~aHHe ~ H30 v I7PE#METHLIB ~A3ATE~L

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v I7PE#METHLIB ~A3ATE~L II3y~eHne nH~eKunOHHuX 3abo~eBaHnn 20 II3~HTHe ~BoTHoro Ha ~KCHepUMeHTa 12-14 IIM6p~nHr 53 n3au~ 20 t,IHCHeKTHpOBaHHe 10 t,IHCHeK~HOHHOe y~paB~eHHe HO OXpaHe ~BOTH~X ~ paCTeHHU (APHIS) 119, 121 t,IHCTHTyT 3a~HTM ~BOTH~X (AWI) 1 1 1- 1 12 t,IHCTHTyT peCypCOB ~a60paTOpH~X ~BOTH~X (ILAR) 3 , 1 5, 115 - 116 t,IH~OpMa~HOHHMU ~eHTp 3a~HTM ~BOTH~X (AWIC) 15, 41, 1 1 1 K KaHa'~cKaH accoUnaU~ rIo Me'~nHcKoMy o6ecrIeHeHHIo ~a6opaTopHux ~BOTH~X (CALAM/ACMAL) 113 KaHa'~cKnn COBeT rIo yxo,~y 3a ~BOTH~MU (CCAC) 15, 1 13- 1 14 KapaHT~H 63-65 CM. TaK*e pa3~e~EHoe co,~ep~aHHe ~ H3o~qU Ke~poBa~ cTpy*Ka 46 K~eTKH ~ pa3Me~eHHe B HUX 25, 40-42 nCTKa ~ CaHuTapHme MepOrip~T~ 26, 46-48 cTpyKTypHme 3JIeMeHTu 29 - 3 2 pa3Mepu ~ pacrIpe~e~eHne upocTpaHcTBa 27-32 rio~m 26, 47 CM. TaK*e IlepB~HMe orpa;K,D;eH~ KneTKu c Kpume~HuMn ~BTpaMn 26, 34-36, 37,65 Kn~H~ecKne 3arIncH 51-52 KOMUCCHU rIo co'~ep~aHHIo ~ ncrIo~B3osaHHIo ~BOTHuX (IACUC) 24, 123 ~ rIpOeKTHpOBaHHe pa3Me~eH~ ~BOTHuX 28-31 peKoMeH~yeMa~ ~nTepaTypa 89 ~ x~pypr~ecKne orIepaLlHn 13, 67 KOMUCCHU CM. KOMUCCHU rIo co'~ep~aHHIo ~ ncrIo~B3osaHHIo ~BOTHuX, (IACUC) KoMHaTHme (~oMa~Hne) ~BoTHme 54 KoMrIBloTepHoe MO,~e~HpOBaHHe KaK a~BTepHaTHBa ncrIo~B3oBaHHIo *HBOTHuX 1 l, 124 ripu ripOeKTupOBaHnn BuBap~ 35, 77 KoHTaM~HaHTM7 rIepeHocHMMe BO3,~ywHuM HyTeM 17-19, 24-27, 35-38, 68-69 B KOpMe 42-44 peKoMeH~yeMa~ ~nTepaTypa 95-96 B BO,~e 45 KOHTPO~B 3a6o~eBaHHn 64-66 KoHueHTpau~ ra30B 24, 37-38 KoHueHTpau~ ~acTu~ 24, 34-36, 37 KopH~opM 17, 79, 84 KOPM lI KOpMJIeHlIe 25-27, 42-45 aBTOK~aB~pOBaHne 43, 45 KopMy~Ku ~ ycTponcTBa 28, 43-44, 47 peKoMeH~yeMa~ ~nTepaTypa 100-102 129

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130 orpaH~eHne rioTpe6~eH~ 13-14, 44 xpaHeHne 43, 84 KOPOBM 29-33, 65 KO~KH 42, 52 Tpe6oBaH~ K pa3Me~eHHIo 28, SO, 34 ripno6peTeHne 62 peKoMeH~yeMa~ ~nTepaTypa 94 KpeMau~ 50 KpHoKoHcepBaLl~ 5 1 - 5 3 KPOJI~KH SO, 34, 44, 48 3a6O~eBaH~ 64-65 peKoMeH~yeMa~ .~nTepaTypa 103-105 KpyrIHMn poraTMn CKOT, rIoTpe6HocTH B lIpOCTpaHCTBe 29, 33, 40-42 KpucM SO, 34, 64-65 a~B6nHH3M ~ ~OTOTOKC~HOCTB 39 3a6O~eBaH~ 64-65, 68 KypM 31, 34 Jl ~eKapCTBeHHMe Cpe~CTBa 1 1 peKoMeH~yeMa~ ~nTepaTypa 103 JlelIeHHe ~ TeparIesT~ecKne rIpoLle'~ypM 65-66 ~oBy~Ku 5 1 Jloma,~n, Tpe6oBaH~ K 3aHUMaeMOMy HpOCTpaHCTBy 34, 42 M MaKaKu 21, 65 MaKpocpe~a 24 Me'~HLl~HcKnn OCMOTp rIepcoHaJIa 20 Me~nHcKoeHa6~0~eHne3anepcoHa~oM~a60paTopun2O, 124-125 KBa~nKau~ ~ no~roToBKa 14-15 peKoMeH~yeMa~ ~nTepaTypa 106-107 CM. TaK*e tHrneHa Tpy,~a ~ 6e3orIacHocTE rIepcoHa~a Me*Be,~OMCTBeHHaH KOMuCC~ rIo 3KcrIepuMeHTa~BHuM ~BOTHuM 123 Me;K~D,yHapo~~HMn COBeT rIO HayKe O JIa6opaTopHux ~BOTHuX (ICLAS) 116 MecTa,~ oT~uxa 25, 27, 28, 40 MeTa6o~ecKne rIpo~eccM 25, 35 M~Kpocpe'~a 24 M~HUCTepCTBO BHyTpeHHUX ~e~ C~A 122 MlIHlICTepCTBO CeJIBCKOrO X03~HCTBa CIIIA (USDA) 62, 119-121 Mnope~aKcaHTu 71 MO~e~HpOBaHHe CM. KOM0BlOTepHOe MO~e~HpOBaHHe Moe~Hme rioMemeH~ 17 MOpCKHe CB~HKH 3O, 46, 65, 66 MOU~OH ~ aKTuBHocTB 42 MoHa 26, 48 MLIIIIII 34, 40 3a6O~eBaH~ 65-66 Tpe60BaH~ K pa3Me~eHHIo 29, 3O, 34 v I7PE#METHLIB ~A3ATE~L

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v I7PE#METHLIB ~A3ATE~L Ha6~o~eHne 17, 2O, 65-66 HacecTu, sucTyr~m 25-28, 40 H ayqHLIlI ~eHTp Sa~HTM ~BOTH~X ~ S CAN 1 19 HaunoHa~bHa~ accounau~q 6noMe~nHcKnx ncc~e~osaHnn (NABR) 1 17 Ha~HOHa~BHMe UHCTHTyTM 3~0pOBB~ (NIH) 16, 18, 2O, 112 HaunoHa~BHun HayqHo-ncc~e~osaTe~BcKnn coseT (NRC) 15, 18, 20 HecqacTHme cyan ~ asapun 18, 19, 51, 65 HeTpa~HOHHMe Bit ~BOTH~X CM. 3K3OTHqeCKHe ~ ~HKHe BOTHER HOMeHK~aTypa 52-53 peKoMeH~yeMa~ JInTepaTypa 98-99 HoqHme ~soTHme 38 H 131 o 06e3B~HM CM. ~pUMaTM 06orameHne open o6nTaH~ 24, 27, 29, 40-42 peKoMeH~yeMa~ ~nTepaTypa 85 060py~osaHne 28-29, 40-41 06yqeHnenrIo~roTosKarIepcoHaJIal4-15, 17-18, 123-125 rIo yMeHEmeHnIo myMa 40 peKoMeH~yeMa~ JInTepaTypa 106-107 6e3orIacHuM rIpoL~e~ypaM 17-18 x~pypraqecK~M rIpoL~e~ypaM 66 06~upHoe x~pypraqecKoe BMe~aTe~ECTBO, He lIplIBO~ee K CMepTH 1 1, 13, 67-68 06meHne c qe~oseKoM 42 06mecTso nH*eHepos-cseToTexH~Kos CesepHon AMep~Ku (IESNA) 39 06~eCTBo mTaTa MaccaqyceTc rho ape, peso ~eCToKoro o6pameH~ c ~BOTH~MU (MSPCA) 117 OBOES 43, 44 OBUM 33, 34, 42 Orpa0;eH~ CM. K}IeTKlI lI pa3MeILleHlIe B HlIX; IlepBlIqHLIe Orpa - ;eH~; BTOplIqHLIe orpa0;eH~ OrpaH~qeHne roped Ka~opun 44 Omega 17-19 Omega O~HOpa3OBOrO HO~3OBaH~ 16 OKHa 79-80 Or~acHme areHTu 15-19 peKoMeH~yeMa~ JInTepaTypa 92-93, 95-96 ~HKB~a~ OTXO~OB 49-50 OcseTuTe~BHme c~cTeMm c TauMepoM 3 8 -39, 83 OCsemeHne 37-39, 83 OT~e~ TIO 3a~HTe OT PUCKa r~pH TIPOBe~eHHU HaYqH~X ~CC~e~OBaHHU 1 1 8 OT~eJI CO6JI]O~eH~ SaKOHOB {IO YXO~Y Sa ~BOTH~MU (REAC) 1 19 OTXO~M 16-19, 47-50 6~0~0r~qeCKH OrIaCHMe 49-50 ~ BHe~HHe YKP~T~ 27 XPaHeHHe 5O, 79, 84 OLIeHKa PUCKa 16

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132 IlaPa3HTEI, JI~TePaTYPa 102 Ilapa~ 71, 124 IlaTO~Or~, ~HTePaTYPa 102-103 IlePB~HMe OrPa~eH~ 25-26 I7PE#METHLIB ~A3ATE~L II HUCTKa ~ CaHUTaPHMe MePOTIP~T~ 46-49 Pa3MePM ~ PaCrIPe~eJIeHHe rIPOCTPaHCTBa 27-32 TIO~M 25 O6OPY~OBaHHe 25, 28-29, 40-41 TeMI1ePaTYPa ~ B~a*HOCTB 32-34 BeHT~SI~ ~ B03~HMU HOTOK 25-27, 35-37 CM. TaK*e K~eTKH ~ pa3Me~eHHe B HlIX Ileper~e~a 3 1 IlePHO~HKa 105-106 IleCHaHKH 34 IlUrMeHTaU~ 38-39 II~TaHHe ~ erO KOHTpO~B 13-14, 42-45 II~TaHHe CM. KOPM ~ KOPM~eHHe Il~aH CrIaCaTe~EH~X MePOrIP~THU 5 1 IIOBe~eHHe ~ erO H3MeHeH~ 2, 11-12, 13, 23, 24, 40-42 IIOBO~OK, HpUBH3B 12 lO~rOTOBKa CM. '~peccHpoBKa ~BOTHuX; 06y~eHHe lI rIO~rOTOBKa nepcoHa~a IO~CT~ 26-27, 33-37, 45-46 CMeHa 26, 31, 37, 46, 48 HKB~aU~ 17-18 IIO3M ~ rIOCTYPa~EHOe rIPUCrIOCO6~eHHe 3, 12-13, 23-24, 27-28, 41-42 IIOKa3aH~ CYXOrO TePMOMeTPa 32, 34 IIO~eBMe ~CC~e~OBaH~ 6 IIOJIKII, BLICTylILI 26, 40 IIO~M 26, 80 B K~eTKaX 26, 47 -48 IIOMe~eH~ 79-87 ,DgISI IIIICTKII lI lIpOBe~eH~ CaHUTapH~X MepOUp~THU 17, 79, 84-85 =H ~KCI1ePUMeHTOB C OTIaCH~MU areHTaMU 17, 79 , 83 PeKOMeH~YeMaH JI~TePaTYPa 94-95 6e3OrIaCHOe rIPOeKTHPOBaHHe ~ 3KC~YaTaLI~ 16-17 ,D~SI HpOBe~eH~ X~pypr~eCKHX oHepa~H 66-69, 85-87 CM. TaK*e K~eTKH ~ pa3Me~eHHe B HUX; Pa3Me~eHHe; Pa3Me~eHHe Ha OTKpLITOM B03~yXe; ~epB~HMe Orpa~eH~; BTOp~HMe Orpa - ;eH~; Tpe60BaH~ K 3aHlIMaeMOMy lIpOCTpaHCTBy IIOHTI 34 OlIa~aHHe B ~OBY~KY, 3aCTPeBaHHe 26-27 IIOCTaB~HKH ~BOTH~X 62-63 IIOCTaHOB~eHHe O 3a~HTe ~BOTH~X (AWRS) 3, 4, 9-11, 119, 121 PeKOMeH~aLIHU {IO Pa3Me~eHHIO ~BOTH~X 25-27 KBa~HKaU~ rIePCOHa~a 16, 66-67 TPaHCI1OPTHPOBKa ~BOTH~X 62 BeTeP~HaPHaH r~oMomB 14 IlOCTaHOB~eH~ 2-4, 9, 12, 64

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v I7PE#METHLIB ~A3ATE~L 133 peKoMeH,~yeMa~ JInTepaTypa 99-100 IIOTO~KH 81 Ilpas~a 2-4 peKoMeH,~yeMa~ JInTepaTypa 99-100 CM. TaK*e IIPOTOKO~M CO~ep~aH~ ~ ~CHO~B3OBaH~ ~BOTH~X paBlIJIa lIepeBO3KH ~BOTH~X Me~yHapO~HOH accounaunn score TpaHcrIopTa (IATA) 62 Ilpas~a rho ryMaHHOMy co,~ep~aHn~o ~ ~CHO~B3OBaHHIO ~abopaTopHux ~IBOTHLIX CJIY*6M 3,~pasooxpaHeH~ (PHS Policy) 3, 9- 1 1, 1 1 8, 123 peKOMeH~a~H HO pa3Me~eHHIO ~BOTH~X 28 o Ksa~nKaunn r~epcoHa~a 14-15, 67 o 6e3or~acHocTn 17 O BeTep~HapHOH HOMO~H 14 pa3~H~HMe ~HU, yXo~ sa ~BOTH~MU 51 IIpa~e~Hme 15-16 Ilpe'~sapuTe~EHme ncc~e'~osaH~ 1 1 IlpecM~Ka~omnec~, peKoMeH,~yeMa~ JI~TepaTypa 90 puMaTO~Or~eCKnn nH~OpMaunOHHun 06MeHHun ~eHTp (PSIC) 118-119 Ilp~MaTO~Or~eCK~ ~H+OpMaunOHHun ~eHTp 118 IIpuMaTu 18, 4O, 8O, 84 K~nH~ecKne 3arIncH 51-52 3a60~esaH~ 19, 65-66 Tpe60BaH~ K pa3Me~eHnIo 28-35 BB03 62-63 peKoMeH,~yeMa~ JInTepaTypa 100 ~nKcaL~ 12 IIP~HUHHM HpaBUTe~BCTBa C~A B OTHO~eHHU HpUMeHeH~ ~ CO~ep~aH~ lI03BOHOIIHEIX ~BOTHEIX, ~CHO~B3yeMBIX B ~CHEITaH~X ncc~e,~osaH~x ~ oGy~eHnn 2, 3, 7, 11, 123-124 IlpH06peTeHHe ~BOTHEIX 62 IIPOBO~O~HEIU H0~ 26, 46 IIPOTOKO~BI 1 1-12 IIPOTOKO~BI CO~ep~aH~ ~ ~CHO~B30BaH~ ~BOTHEIX 1 1-12 Ilpo~eccuoHa~sHEIe o6mecTsa 11, 108-120 IITTIUBI, peKOMeH~yeMaH ~HTepaTypa 94 Hyp~Ha Mu~nc, ~HK. 119 p Pa~Ha~H 16,17,50 Pa3Be~eHne ~ pa3MHo~eHne 51,62 yc~oBu~ oKpy~aIor~en cpe~I 24-27 perucTpaun~ 51-52 Pa3~e~Hoe co~ep~aHne ~ n30~ 50-51,63-65,79 Pa3Mer~eHne 25,124 ~aKTOp~I, y~nT~IBaeM~Ie upu n~aHupOBaHnn 23-24 6e3OnacHoenpoeKTupoBaHne 17 CM. TaK*e KneTKH ~ pa3Me~eHHe B HuX; pa3Me~eHHe Ha OTKpLITOM so3,~yxe; IlepB~HEIe Orpa;K,D;eH~; BTop~HEIe Orpa;K,D;eH~; Tpe6oBaH~ K 3aHuMaeMoMy rIpocTpaHcTBy; ~ KOHKpeTHEIe B~BI ~BOTHEIX

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134 Pa3MHO*eHHe CM. Pa3Be~eHHe ~ pa3MHO*eHHe PerUCTpa~ ~ ~e~OUpOH3BO~CTBO B ~HH~Ke 51-52 reHeT~eCKHe 3aHUcH 52-53 ~eHTu~nKau~ 51-52 PeMoHT ~ aKc~yaTau~ 26, 37 Pe~HpKy~Hpylo~H B03~HMU HOTOK 36-37, 82-83 Po~oc~oBHa~ 53 Pu6m, peKoMeH~yeMa~ ~nTepaTypa 90 C CaHUTap~ CM. 9HCTKa ~ CaHUTapHMe MepOUp~T~ CBeT 37-3 8, 83 CB~HB~, 3a6o~eBaH~ 65 Tpe60BaH~ K 3aHUMaeMOMy HpOCTpaHCTBy 27, 3 2 Ce~aTuBHun a~eKT ~ cede cpe~cTBa 13, 71 Ce~BcKoxo3~ncTBeHHme ~BoTHme 4-5, 50 Tpe60BaH~ K pa3Me~eHHIo 5, 3 2- 34, 42 peKoMeH~yeMa~ ~nTepaTypa 97-98 XlIpyprWIeCKlIe rIpO~e~ypM 69, 85 Ce~BcKoxo3~ncTBeHHme ncc~e~oBaH~ 4, 5 CHCTeMa OTO~eH~, BeHT~q~H ~ KOH~HOHUpOBaH~ so3~xa (HVAC) 36, 82-83 CKOpOHOpTSI~HeCSI KOpMa 43 cobaKu 11-12, 41-42, 50-52 Tpe6oBaH~ K pa3Me~eHHIo 26, 27-31, 34, 42 ripno6peTeHne 62 peKoMeH~yeMa~ ~nTepaTypa 94 coBeT ABcTpa~n ~ HOBOH 3e~aH~n rIo co'~ep~aHHIo ~BOTHuX, ncrIo~B3yeM~x B HayqHuX nCC~e,~OBaH~X ~ o6yqeHHn (ANZCCART) 112- 1 13 co'~ep~aHHe ~BOTHuX 2, 3, 40-52 Ha OTKpuTOM Bo3~yxe 26-27 peKoMeH,~yeMa~ JInTepaTypa 99 CM. TaK*e IIO,~CT~; 9HCTKa ~ CaHUTapHMe MepOUp~T~; KOPM KopM~eHHe; perucTpa~ H'~e~orIpon3Bo'~cTBo; peMoHT 3KCIIJIyaTa~ co'~ep~aHHe Ha OTKpuTOM Bo3~yxe 26-27 aKK~uMaTu3au~ 27, 34 60pE6a C Bpe~HTe~MU 50 nCTOqH~KH BO,~M 45 co~Ha~EHMe rpyr~rIM ~ CO~Ha~EHMe B3aHMO~eUCTB~ 23-29, 41-42 CPOK XpaHeH~ KOpMa 43 CTeHm 8 1 CTep~3au~ ~eToK ~ obopy~oBaH~ 25, 47 -49 KopMa 44 OrIaCHuX OTXO,~OB 50 =H rIPOBe ~eH~ X~PYPrOqeCKHX {IPOLle ~YP 6 8 CTPOUTe~BHEIe MaTePHa~BI 25, 78 CY6K~HH0qeCKHe UH~eKUHU 65 CYTOqHEIe LI~K~BI 3 8 - 3 9 v I7PE#METHLIB ~A3ATE~L

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I7PE#METHLIB ~A3ATE~L T TeMrIePaTYPa 24, 25, 32-34, 82-83 Tempo 32-34 TeTaHYC 20 TOHHe~H 40 TPaHCreHHMe BOTHER 52-53 TpaHcrIopTHpoBKa ~BOTHuX 62 TPe60BaH~ K 3aHUMaeMOMY {IPOCTPaHCTBY 27 - 3 0, 3 1 - 3 3, 42 TpyrIm, JI~KB~aLI~ SO, 79, 84 TY6ePKYJIe3 20, 63 THra 35 y YKP~T~ 26 YKYCM ~ LIaParI~HM 14-15, 18-19 yHuBepcHTeTcKaH ~e,~epa~ vaunts ~BOTHuX (UFAW) 1 19 YI1PaB~eHHe rho OXPaHe ,~nKHX ~BOTHuX ~ pub 64, 122 YCJIOB~ oKpy~alo~en cpe,~M 24-40 eCTeCTBeHHMe {IO CPaBHeHHIO C KOHTPOJI~PYeMMMU 4, 24, 27 CM. TaK*e IIOMe~eH~; Pa3Me~eHHe ycTponcTBa,=H TyaJIeTa 28 135 q) aPMaKOJIOr~, PeKOMeH,~YeMaH JI~TePaTYPa 103 ~3~0~0r~eCKaH ~YHKU~ 1 1 - 1 2, 24- 26 ~3~eCKaH aKTHBHOCTB 41-42 ~3~eCKaH OrIaCHOCTE 15-17 HKCaU~ 12-13 ~BTpM HEPA (B~COKO8~eKTHBHMe BO3~Y~HMe ~~BTPM ~H OHUCTKH OT KOPrIYCKYMqPH~X rIPUMeCeH) 36-37, 82 KOHL 6HOMe ~~HHCKHX OCCUR ~OBaHHU ~ FB R) 1 1 5 OTOrIePHO~ 37-38, 81 OTOCTPeCCOP 38 OTOTOKC~eCKaH PeTHHOrIaT~ 38 X X~M~eCKHe MOJO~He CPe~CTBa 17, 48, 68 x~pypr~ecKne rIpoLle'~ypM 12-14, 66-70, 124 aBTOK~aB~POBaHHe 68, 86 rIOMe~eH~ 68-71, 85-87 KOHTPOJIB 66 seethe rIocJIeorIepaLlHoHHoro rIepHo'~a 7O, 86-87 peKoMeH,~yeMa~ JI~TepaTypa 90-91 XOM~KH 3 0, 34, 49 XPaHeHHe rIPH HH3KHX TeMrIePaTYPaX ~ 3aMOPa~BaHHe 32, SO, 85 XPaH~a ~ KOHTe~HePLI 79, 84 =H KOPMa ~ rIO~CT~a 43-44, 84 =H OTXO~OB SO, 79, 84

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136 v I7PE#METHLIB ~A3ATE~L He~Hun Don 26, 48 ~eHTp a~BTepHaTHBHEIX MeTO~OB, 3aMeHRIO~UX ~CHO~B30BaHHe ~BOTHEIX (CAAT) 114 ~eHTp 3a~HTEI ~a60paTOpHEIX ~BOTHEIX (C~ 117 ~eHTp HO KOHTpO~IO ~ Hpo~aKT~Ke 3a6o~eBaHHn (CDC) 18-20 0HpKa~HEIe PI 3 8, 3 9 II ~e~OBeKO06pa3HEIe 06e3~HHEI CM. ~pUMaTEI HucTKa ~ cape Meponp~T~ 17, 29, 37, 46-49, 79, 80-81 III IIIyM 19, 39-4O, SO, 84 3nTaHa3~ 11, 72-73 peKoMeH~yeMa~ ~nTepaTypa 96 ~ x~pypr~ecKne Crepe 68 3K30T~ecKne ~ Ankle ~BoTH~Ie 5-6, 29 ncHe3aI0~He BALI 62 peKoMeH~yeMa~ ~nTepaTypa 96-97 3KCriepuMeHT~I, CB~3aHH~Ie C B~Ipa60TKOn yC~OBH~IX pe~eKCOB 14 3~eKTp~ecTso 83 3~eKTpoc~cTeM~I 83 3proHoM~Ka 17 Extra, peKoMeH~yeMa~ ~nTepaTypa 96 Coup 19 peKoMeH~yeMa~ ~nTepaTypa 95

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~OHO~HUT~b~ ~HTEPATYPA C~e~y~omne ~6~HKa~H HMelOTCH B paCHOpH*eHHU H3~aTe~ECTBa HaunoHa~Hon aKa~eMun: National Academy Press, 2101 Constitution Av- enue, NW, Lockbox 285, Washington, DC 20055 (Te~. 1-800-624-6242 ~n 202-334-3313~. IIHTepHeT: http://www.nap.edu. KpoMe Toro pas~Hme r~y6~nKaunn, so e~eKsapTa~Hun <>, HMelOTCH B paCHOp~eHHU ~HCTHT~a peC~COB ~a60paTOpH~X soTHux (Te~.: 202-334-2590; Isaac: 202-334-1687; an. Aorta: ILAR@nas.edu; URL: http://www.2.nas.edu/ilarhome/~. Occupational Health and Safety in the Care and Use of Research Animals. Forth- coming Psychological Well-Being of Nonhuman Primates. Forthcoming Rodents: Laboratory Animal Management Series. Forthcoming Nutrient Requirements of Laboratory Animals, Fourth Revised Edition. 1995 Dogs: Laboratory Animal Management Series. 1994 Nutrient Requirements of Poultry, Ninth Revised Edition. 1994 Nutrient Requirements of Fish. 1993 Recognition and Alleviation of Pain and Distress in Laboratory Animals. 1992 Education and Training in the Care and Use of Laboratory Animals: A Guide for Developing Institutional Programs. 1991 Infectious Diseases of Mice and Rats. 1991 Companion Guide to Infectious Diseases of Mice and Rats. 1991 Immunodeficient Rodents: A Guide to Their Immunology, Husbandry, and Use.1989 Nutrient Requirements of Swine, Ninth Revised Edition. 1988 Use of Laboratory Animals in Biomedical and Behavioral Research. 1988 Vitamin Tolerances of Animals. 1987 Nutrient Requirements of Cats, Revised Edition. 1986 137

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138 Nutrient Requirements of Dogs. 1985 Nutrient Requirements of Sheep, Sixth Revised Edition. 1985 Nutrient Requirements of Goats. 1981 Nutrient Requirements of Nonhuman Primates. 1978 Nutrient Requirements of Rabbits. 1977