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Appendix Hematopoietic Cell Surface Antigens Mentioned in the Text Cluster of Monoclonal Antibodies Reacting to Species Differen- Specific Cell Surface Antigen tiation (CD) Designation Human Mouse Rat Guinea Pig Hamster Distribution Description CD 1 T6 Ly-38 Langerhans' Cortical Leu-6 cells, thymocyte OKT6 thymocytes differentiation marker CD2 T11 Ly-37 OX34 All T cells E-rosette OKT11 forming E receptor Leu-Sb ' rosettes, NK cells CD3 T3 Mature T cells Constant portion OKT3 of Ti receptor Leu-4 CD4 T4 Ly-4 OX36 Helper/ A member of the OKT4 L3T4 OX37 inducer T class II Leu-3a OX38 lymphocytes restricted T W3/25 cell population OX35 CD5 T1 Ly-1 R-1-3133 8BE6 T cells, B-cell OKT1 Lyt-1 OX19 subset Leu- 1 CD6 T12 Mature T cells, Subpopula tion of B cells Continued 213
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2 14 APPENDIX Hematopoietic Cell Surface Antigens Mentioned in the Text (continued) Cluster of Differen- tiation (CD) Designation Monoclonal Antibodies Reacting to Species- Specific Cell Surface Antigen Human Mouse Rat Guinea Pig Hamster Distribution Description CD8a T8 OKT8 Leu-2a Leu-2b CD8b CD1 la CD1 lb CD16 CD20 OX8 OX9 OX10 Ly-3 Lyt-3 LFA- 1 Ly- 15 Mac- 1 Ly-40 OX42 Leu-15 Leu-1 la B1 Leu-lb CD23 CD23 Ly-42 CD25 TAC IL-2R CD32 FcRI, CD45 T29/35 CT6 Ly-43 OX39 SC3 ? ART-18 Ly-17 Lym-20 Ly-5 OX22 201 T200 L-CA CD45R CD45R Ly-5 OX5 1 B220 Transferrin OKT9 OX26 receptor Cytotoxic T CTL adhesion lymphocytes (CTL) CTL CTL adhesion Leukocytes and erythroid and myeloid stem cells Macrophages. C3bi receptor granulocytes. Ly-1 B cells NK cells. FcRlo granulocytes B lymphocytes except plasma cells; follicular dendritic cells B lymphocyte IgE Fc receptor subsets. follicular dendritic cells Activated T cells. B cells B. myeloid. and Langerhans' cells Panleukocyte. erythroblast. and follicular dendritic cells; thymocytes; and some B cells Pre-B and B cells. CTL. granulocytes. monocytes Activated lymphocytes. monocytes IL-2 receptor Fc IgG2b/1 receptor
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APPENDIX 2 15 Hematopoietic Cell Surface Antigens Mentioned in the Text (continued Cluster of Monoclonal Antibodies Reacting to Species Differen- Specific Cell Surface Antigen tiation (CD) Designation Human Guinea Mouse Rat Pig Hamster Distribution Description Theta Thy- 1 Thy- 1 OX7 Thy- 1 Ia HLA-D H-2I RT1B (DR, (I-A, RT1D DP, DQ) I-E Others 154 Lyb-3 Lyb-7 Lyb-5 ThB OX2 HO-13-4 T cells? Not present on neurons. human T cells f~broblasts, and stem cells B cells, MHC class II monocytes. (Ia) antigens activated T cells B cells B and T lymphocytes, subsets of thymocytes. 15% of bone marrow cells B lymphocyte subset B lymphocytes. thymocytes Follicular dendritic cells P51 S11 S12 S34 SOURCES: Murine hematopoietic cell surface antigen expression? K. L. Holmes and H. C. Morse III, eds., Immunol. Today 9:344-349, 1988. The Lymphocyte: Structure and Function, 2d ea., J. J. Marchalonis, ea., Marcel Dekker, Inc., New York, 419 pp., 1988. Differentiation Antigens in Lymphohemopoietic Tissues, M. Miyasaka and Z. Trnka, eds., Marcel Dekker, Inc., New York, 531 pp., 1988.
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