TABLE 10-1 Effects of Jet Fuel Exposure on the Cardiovascular System in Humans and Experimental Animals

Fuel Type


Exposure Concentration

Exposure Duration




Human, 5,706 exposed subjects and 5,706 unexposed subjects

Exposed group had potential occupational exposure to JP-8; control group did not work in occupations in which exposure to JP-8 would occur

Not reported

Medical records showed no increase in medical visits related to cardiovascular events

Gibson et al. 2001aa


Human, 328 individuals

Measurements taken in breathing zones of subjects; median concentration of naphthalene, 1.9 μg/m3 (low-exposure group), 10.4 μg/m3 (moderate-exposure group), 447 μg/m3 (high-exposure group); median concentration of benzene, 3.1 μg/m3 (low-exposure group), 7.45 μg/m3 (moderate-exposure group), 242 μg/m3 (high-exposure group)

High- and moderate- exposure groups had persistent exposure to JP-8 (defined as at least 1 hr twice per wk for at least 9 mo); low-exposure group had no significant exposure to jet fuel or solvents

Data collected from self-assessment questionnaire; subjects in moderate- and high-exposure groups reported more heart palpitations and chest tightness than subjects in low-exposure group; odds ratios for subjects in moderate-exposure group, but not high-exposure group, were significantly greater than for low-exposure group

Gibson et al. 2001ba

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