TABLE 10-1 Effects of Jet Fuel Exposure on the Cardiovascular System in Humans and Experimental Animals

Fuel Type

Species

Exposure Concentration

Exposure Duration

Effects

Reference

JP-8

Human, 5,706 exposed subjects and 5,706 unexposed subjects

Exposed group had potential occupational exposure to JP-8; control group did not work in occupations in which exposure to JP-8 would occur

Not reported

Medical records showed no increase in medical visits related to cardiovascular events

Gibson et al. 2001aa

JP-8

Human, 328 individuals

Measurements taken in breathing zones of subjects; median concentration of naphthalene, 1.9 μg/m3 (low-exposure group), 10.4 μg/m3 (moderate-exposure group), 447 μg/m3 (high-exposure group); median concentration of benzene, 3.1 μg/m3 (low-exposure group), 7.45 μg/m3 (moderate-exposure group), 242 μg/m3 (high-exposure group)

High- and moderate- exposure groups had persistent exposure to JP-8 (defined as at least 1 hr twice per wk for at least 9 mo); low-exposure group had no significant exposure to jet fuel or solvents

Data collected from self-assessment questionnaire; subjects in moderate- and high-exposure groups reported more heart palpitations and chest tightness than subjects in low-exposure group; odds ratios for subjects in moderate-exposure group, but not high-exposure group, were significantly greater than for low-exposure group

Gibson et al. 2001ba



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