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. "2. Prion Diseases and Their Challenges." Advancing Prion Science: Guidance for the National Prion Research Program -- Interim Report. Washington, DC: The National Academies Press, 2003.
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TABLE 2-1 Classification of TSEs
Type of TSE
Modes of Natural Transmission
Date First Recognized
Sporadic Creutzfeldt-Jakob disease (sCJD)
Sporadic fatal insomnia (sFI)
Familial Creutzfeldt-Jakob disease
Fatal familial insomnia (FFI)
Exposure to contaminated human tissues during endocannibalistic rituals
latrogenic Creutzfeldt-Jakob disease
CJD-infected surgical equipment or tissue transplants
Variant Creutzfeldt-Jakob disease (vCJD)
Eating BSE-infected tissue; other modese