TABLE 2-1 Classification of TSEs

Type of TSE

Affected Mammals

Modes of Natural Transmission

Date First Recognized

In humans

Sporadic Creutzfeldt-Jakob disease (sCJD)

 

Unknown

1920

Sporadic fatal insomnia (sFI)

Unknown

1999

Familial Creutzfeldt-Jakob disease

Genetic

1924a

Fatal familial insomnia (FFI)

Genetic

1986b

Gerstmann-Straussler-Scheinker disease

Genetic

1936c

Kuru

Exposure to contaminated human tissues during endocannibalistic rituals

1957

latrogenic Creutzfeldt-Jakob disease

CJD-infected surgical equipment or tissue transplants

1974d

Variant Creutzfeldt-Jakob disease (vCJD)

Eating BSE-infected tissue; other modese

1996



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement