TABLE 4-3 Epidemiologic Studies—Veterans' Exposure

Reference

Study Design

Description

Study Group (N)

Comparison Group (N)a

UNITED STATES STUDIES

New Ranch Hand Studies

Michalek et al., 2001a

Cohort

Based on physical examination through 1992 and medical records reviewed through March of 1993; analyzed association between serum dioxin levels and hepatic abnormalities

931

1,199

Michalek et al., 2001b

Cohort

Based on physical examination in 1982, 1985, 1987, 1992, and 1997 and medical records through 1997; analyzed association between serum dioxin levels and peripheral neuropathy

926

918

872

834

761

1,067

1,144

1,131

1,110

1,086

Michalek et al., 2001c

Cohort

Based on physical examination in 1982, 1985, 1987, and 1992 and medical record through 1997; analyzed association between serum dioxin levels and hematological function

1,046

1,017

996

953

1,223

1,292

1,298

1,280

Barrett et al., 2001

Cohort

Based on tests of cognitive function in 1982, and dioxin levels measured in 1987 and 1992; analyzed association between serum dioxin levels and cognitive function

937

1,052



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