Appendix E
Systems Physiology Experiments Planned for the ISS

Experiment Number

Experiment Title

Investigator

Target Mission (if known)

NASA-Sponsored ISS Flight Experiments into Calendar Year 2004

96-01-507

Human Orientation and Sensory Motor Coordination in Microgravity

A. Berthoz

Incr. 8-10 (6 Sz)

98-02-120

Promoting Sensorimotor Response Generalizability During Inflight Treadmill Exercise: A Countermeasure to Mitigate Locomote Dysfunction After Long-Duration Space Flight

Jacob J. Bloomberg

Incr. 5-9 pre/post only,

Incr. 10 in-flight

99-03-046/99-03-377

Human Cardiovascular Performance in the Space Flight Environment

Michael Bungo, Ben Levine

Not manifested

96-04-318

Foot Reaction Forces During Spaceflight

P.R. Cavanagh

Incr. 6 (launch ULF1)

96-04-400

Effect of Prolonged Spaceflight on Human Skeletal Muscle

R.H. Fitts

Incr. 5, 6, 7, 8, 9

96-04-290

Effects of Microgravity on the Peripheral Subcutaneous Veno-Arteriolar Reflex in Humans

A. Gabrielsen

Incr. 3-4 (7A.1)

96-01-096

Crew Member and Crew-Ground Interactions During International Space Station Missions

N. Kanas

Incr. 2-5, 7-10

96-04-343

Sub-regional Assessment of Bone Loss in the Axial Skeleton in Long-term Space Flight

T.F. Lang

Incr. 4-8

99-03-370

Influence of Sensory Integration on the Neural Processing of Gravito-inertial Cues

Dan Merfeld

Inc. 14

99-03-010 DSO TBD

Chromosomal Aberrations in Blood Lymphocytes of Astronauts

Gunter Obe

Incr. 6-7

96-01-085

Human Orientation and Sensory Motor Coordination in Microgravity

C.M. Oman (co-I with Berthoz)

Incr. 10-12

99-03-049 DSO TBD

A Comprehensive Characterization of Microorganisms and Allergens in Spacecraft Environment

D.L. Pierson

TBD

96-04-094

Dosimetric Mapping

G.F. Reitz,

Incr. 2

98-02-497

Effects of Resistance Training, using Fly-Wheel Technology, on Size and Function of Skeletal Muscle in Crew Stationed in Space

Per A. Tesch

Not manifested

96-04-011

A Study of Radiation Doses Experienced by Astronauts in EVA

I. Thomson

Incr. 4, 5, 6

96-04-082

Effects of Altered Gravity on Spinal Cord Excitability

D.G.D. Watt

Incr. 2-4 (5A.1)

96-04-044

The Effects of EVA and Long-term Exposure to Microgravity on Pulmonary Function

J. West

Incr. 3-5, 7 (7A.1)



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Factors Affecting the Utilization of the International Space Station for Research in the Biological and Physical Sciences Appendix E Systems Physiology Experiments Planned for the ISS Experiment Number Experiment Title Investigator Target Mission (if known) NASA-Sponsored ISS Flight Experiments into Calendar Year 2004 96-01-507 Human Orientation and Sensory Motor Coordination in Microgravity A. Berthoz Incr. 8-10 (6 Sz) 98-02-120 Promoting Sensorimotor Response Generalizability During Inflight Treadmill Exercise: A Countermeasure to Mitigate Locomote Dysfunction After Long-Duration Space Flight Jacob J. Bloomberg Incr. 5-9 pre/post only, Incr. 10 in-flight 99-03-046/99-03-377 Human Cardiovascular Performance in the Space Flight Environment Michael Bungo, Ben Levine Not manifested 96-04-318 Foot Reaction Forces During Spaceflight P.R. Cavanagh Incr. 6 (launch ULF1) 96-04-400 Effect of Prolonged Spaceflight on Human Skeletal Muscle R.H. Fitts Incr. 5, 6, 7, 8, 9 96-04-290 Effects of Microgravity on the Peripheral Subcutaneous Veno-Arteriolar Reflex in Humans A. Gabrielsen Incr. 3-4 (7A.1) 96-01-096 Crew Member and Crew-Ground Interactions During International Space Station Missions N. Kanas Incr. 2-5, 7-10 96-04-343 Sub-regional Assessment of Bone Loss in the Axial Skeleton in Long-term Space Flight T.F. Lang Incr. 4-8 99-03-370 Influence of Sensory Integration on the Neural Processing of Gravito-inertial Cues Dan Merfeld Inc. 14 99-03-010 DSO TBD Chromosomal Aberrations in Blood Lymphocytes of Astronauts Gunter Obe Incr. 6-7 96-01-085 Human Orientation and Sensory Motor Coordination in Microgravity C.M. Oman (co-I with Berthoz) Incr. 10-12 99-03-049 DSO TBD A Comprehensive Characterization of Microorganisms and Allergens in Spacecraft Environment D.L. Pierson TBD 96-04-094 Dosimetric Mapping G.F. Reitz, Incr. 2 98-02-497 Effects of Resistance Training, using Fly-Wheel Technology, on Size and Function of Skeletal Muscle in Crew Stationed in Space Per A. Tesch Not manifested 96-04-011 A Study of Radiation Doses Experienced by Astronauts in EVA I. Thomson Incr. 4, 5, 6 96-04-082 Effects of Altered Gravity on Spinal Cord Excitability D.G.D. Watt Incr. 2-4 (5A.1) 96-04-044 The Effects of EVA and Long-term Exposure to Microgravity on Pulmonary Function J. West Incr. 3-5, 7 (7A.1)

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Factors Affecting the Utilization of the International Space Station for Research in the Biological and Physical Sciences Experiment Number Experiment Title Investigator Target Mission (if known) 96-01-057 DSO 633 Renal Stone Risk During Space Flight: Assessment and Countermeasure Validation P.A. Whitson Incr. 3-10 (7A.1), STS-107, STS-113, R-2 SMO 008 Entry Monitoring Meck Incr. 8 SMO 006 Test of Midodrine as Countermeasure against Postflight Orthostatic Hypotension Meck Incr. 5, STS-108, 110, 111, 112, 109 NASA-Sponsored ISS Flight Monitoring MR085L Neurocognitive Assessment (SCAT)   All MR077L Physical Fitness Assessment All MR021L Crew Microbiology All MR016L Inflight weekly food frequency questionnaire All MR024L Body Mass Measurement All MR018L Inflight urinalysis/hematocrit All MR003L Radiation Biodosimetry All NASA-Sponsored ISS Pre/Post Flight Testing MR035L Bone Densitometry   All MR001L Operational Tilt Test All MR071L Holter Monitoring All MR010L Clinical Laboratory Assessment All MR077L Isokinetic Dynamometry/FASTEX All MR042L Functional Neurological Assessment All Russian Flight Experiments MBI-1 Study of human body fluids under conditions of long-duration spaceflight   MBI-3 Study of peridontal tissue conditions under spaceflight conditions MBI-4 Study of pharmacological influences under long-duration space mission conditions MBI-5 Intergrated study of the dynamics of the primary parameters of cardiac activity and blood circulation, using a lower body negative pressure (LBNP) apparatus MBI-8 Study of the action mechanism and efficacy of various countermeasures aimed at preventing locomotion system disorders in weightlessness MBI-9 Study of autonomic regulation of the human cardiovascular system in weightlessness RBO-1 Development of a method for real-time prediction of dose loads on the crews of manned space missions

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Factors Affecting the Utilization of the International Space Station for Research in the Biological and Physical Sciences Experiment Number Experiment Title Investigator Target Mission (if known) RBO-2 Bioradiation dosimetry during spaceflight     Russian Pre/Post Flight Experiments Motor control Study of hypo-gravitational ataxia syndrome     MION Impact of microgravity on muscular characteristics     Isokinez Microgravity impact on voluntary muscular contraction. Human motor system readaptation to gravitation     Tendometria Micrgravity impact on induced muscular contraction. Long-duration spaceflight impact on the muscular and peripheral nervous apparatus     Ravonvesie Sensory and motor mechanisms in vertical posture control after long-duration exposure to microgravity     Sensory adaptation Countermeasures and correction of adaptation to space syndrome and of motion sickness     Lokomotsii Kinematic and dynamic locomotion characteristics prior to and after spaceflight     Peregruzki G-forces on Soyuz and recommendations for anti-G force countermeasure development     Polymorphism Genotype parameters related to human individual tolerance to spaceflight conditions     Thermographia Human peripheral thermoregulation during readaptation after long-duration spaceflight     Khemoluminomer Spaceflight factors impact on free-radical oxidation level, as well as changes in human organism during readaptation to Earth conditions     NOTE: Table includes experiments in all areas of systems physiology including cardiovascular studies and musculoskeletal studies, which are also broken out separately in Appendixes F and G.