Reference

Description

Study Group (N)

Comparison Group (N)

Exposure Assessment and Other Relevant Exposures

Analysis and Adjustment for Potential Confounders

Trichloroethylene

Aircraft and Aerospace Workers

Garabrant et al., 1988

Mortality experience (1958–1982) of aircraft-manufacturing workers (at least 1 day) at an aircraft-manufacturing facility in San Diego County, California (with at least 4 years of cumulative company employment)

14,067 total

11,898 men

2169 women

US general population

Employment determined through company work records and interviews

SMR

Age, sex, race, calendar year, duration of employment, year of death

Spirtas et al., 1991

Mortality experience (1952–1982) of aircraft-maintenance workers (at least 1 year in 1952–1956) at Hill Air Force Base in Utah

14,457 total

10,730 men

3727 women

Utah white population

Industrial hygienist assessment from interviews, surveys, hygiene files, position descriptions

SMR, trend analysis

Age, sex, calendar period

 

Other exposures: Stoddard solvent, isopropyl alcohol, trichloroethane, acetone, toluene, MEK, methylene chloride

 

Blair et al., 1998

Incidence and mortality experience (1952–1990) of aircraft-maintenance workers (at least 1 year in 1952–1956) at Hill Air Force Base in Utah

14,457 total

10,730 men

3727 women

Utah white population

Industrial hygienist assessment from interviews, surveys, hygiene files, position descriptions

SMR, RR (Poisson)

Age, sex, calendar period

 

Other exposures: Stoddard solvent, isopropyl alcohol, trichloroethane, acetone, toluene, MEK, methylene chloride

 

Morgan et al., 1998

Mortality experience (1950–1993) of aerospace workers (at least 6 months) Hughes Aircraft plant in Arizona

20,508 total

(4733 exposed)

13,742 men

6766 women

US general population

Exposure matrixes generated by employees and industrial hygienists

SMR, Cox proportional hazards model

Age, sex



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement