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Reference
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Description
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Study Group (N)
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Comparison Group (N)
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Exposure Assessment and Other Relevant Exposures
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Analysis and Adjustment for Potential Confounders
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Trichloroethylene
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Aircraft and Aerospace Workers
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Garabrant et al., 1988
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Mortality experience (1958–1982) of aircraft-manufacturing workers (at least 1 day) at an aircraft-manufacturing facility in San Diego County, California (with at least 4 years of cumulative company employment)
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14,067 total
11,898 men
2169 women
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US general population
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Employment determined through company work records and interviews
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SMR
Age, sex, race, calendar year, duration of employment, year of death
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Spirtas et al., 1991
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Mortality experience (1952–1982) of aircraft-maintenance workers (at least 1 year in 1952–1956) at Hill Air Force Base in Utah
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14,457 total
10,730 men
3727 women
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Utah white population
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Industrial hygienist assessment from interviews, surveys, hygiene files, position descriptions
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SMR, trend analysis
Age, sex, calendar period
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|
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Other exposures: Stoddard solvent, isopropyl alcohol, trichloroethane, acetone, toluene, MEK, methylene chloride
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|
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Blair et al., 1998
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Incidence and mortality experience (1952–1990) of aircraft-maintenance workers (at least 1 year in 1952–1956) at Hill Air Force Base in Utah
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14,457 total
10,730 men
3727 women
|
Utah white population
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Industrial hygienist assessment from interviews, surveys, hygiene files, position descriptions
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SMR, RR (Poisson)
Age, sex, calendar period
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|
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Other exposures: Stoddard solvent, isopropyl alcohol, trichloroethane, acetone, toluene, MEK, methylene chloride
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|
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Morgan et al., 1998
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Mortality experience (1950–1993) of aerospace workers (at least 6 months) Hughes Aircraft plant in Arizona
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20,508 total
(4733 exposed)
13,742 men
6766 women
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US general population
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Exposure matrixes generated by employees and industrial hygienists
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SMR, Cox proportional hazards model
Age, sex
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