Reference

Study Population

Exposed Cases

Estimated Relative Risk (95% CI)

Benzene

Case-Control Studies

Pesch et al., 2000a

Participants in multiple centers in Germany

 

 

 

British job-exposure matrix

 

 

 

Benzene (males)

 

 

 

Medium

95

1.1 (0.8–1.4)

 

High

70

0.9 (0.7–1.2)

 

Substantial

47

1.5 (1.0–2.1)

 

Benzene (females)

 

 

 

Medium

21

1.2 (0.7–2.0)

 

High

18

1.5 (0.9–2.8)

 

Substantial

8

1.4 (0.6–3.3)

 

German job-exposure matrix

 

 

 

Benzene (males)

 

 

 

Medium

177

1.1 (0.9–1.3)

 

High

169

1.2 (1.0–1.6)

 

Substantial

68

1.2 (0.8–1.6)

 

Benzene (females)

 

 

 

Medium

27

1.0 (0.7–1.7)

 

High

23

0.8 (0.5–1.4)

 

Substantial

5

0.6 (0.2–1.6)

 

Job task-exposure matrix approach

 

 

 

Benzene (males)

 

 

 

Medium

51

0.7 (0.5–1.0)

 

High

71

1.0 (0.7–1.3)

 

Substantial

37

1.4 (0.9–2.1)

 

Benzene (females)

 

 

 

Medium

2

0.4 (0.1–1.8)

 

High

3

0.4 (0.1–1.2)

 

Substantial

2

0.8 (0.2–3.7)

Gérin et al., 1998

Male residents of Montreal, Canada

 

 

 

Low exposure

65

1.0 (0.7–1.3)

 

Medium exposure

22

1.2 (0.7–2.0)

 

High exposure

2

0.2 (0.0–0.6)

Toluene

Cohort Study—Incidence

Svensson et al., 1990

Male rotogravure printers in Sweden, employed >3 months

 

 

 

Bladder and kidney cancer

4

0.64 (0.18–1.65)

 

≥5 yrs exoposed with >10 yrs latency

4

0.85 (0.23–2.16)

Cohort Study—Mortality

Wiebelt and Becker, 1999

Male German rotogravure printers, employed >1 year

2

0.66 (0.08–3.27)

Walker et al., 1993

Shoe manufacturers in two plants in Ohio, potentially exposed to toluene and other solvents

 

 

 

Total

7

0.99 (0.40–2.05)

 

Males

4

0.87 (0.24–2.25)

 

Females

3

1.20 (0.25–3.51)



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