Reference

Study Population

Exposed Cases

Estimated Relative Risk (95% CI)

Benzene

Case-Control Study

Gérm et al., 1998

Male residents of Montreal, Canada

 

Low exposure

27

1.2 (0.7–1.9)

 

Medium or high exposure

12

1.3 (0.7–2.4)

Toluene

Cohort Studies—Mortality

Wiebelt and Becker, 1999

Male German rotogravure printers, employed >1 year

2

0.49 (0.06–2.34)

Walker et al., 1993

Shoe manufacturers in two plants in Ohio, potentially exposed to toluene and other solvents

 

 

Total

9

1.36 (0.62–2.59)

 

Males

6

1.71 (0.62–3.73)

 

Females

3

0.97 (0.20–2.84)

Case-Control Study

Gérin et al., 1998

Male residents of Montreal, Canada

 

Low exposure

17

0.9 (0.5–1.5)

 

Medium or high exposure

8

1.0 (0.5–2.1)

Xylene

Case-Control Study

Gérin et al., 1998

Male residents of Montreal, Canada

 

Low exposure

17

1.0 (0.6–1.7)

 

Medium or high exposure

6

1.0 (0.4–2.4)

Isopropyl Alcohol

Cohort Study—Mortality

Alderson and Rattan, 1980

Male UK isopropyl manufacturers, employed >1 year

2

6.45 (0.78–23.29)a

Unspecified Mixtures of Organic Solvents

Cohort Study—Incidence

Anttila et al., 1995

Finnish workers monitored for exposure

 

Halogenated hydrocarbons

7

0.89 (0.36–1.82)

Cohort Studies—Mortality

Boice et al., 1999

Aircraft-manufacturing workers in California

 

Mixed solvents, routine exposure

14

0.81 (0.44–1.36)

 

Years exposed

 

 

<1

11

1.54 (0.74–3.20)

 

1–4

19

1.08 (0.58–2.01)

 

≥5

14

0.41 (0.20–0.82)

Steenland and Palu, 1999

US painters and other union members

 

Painters

100

1.06 (0.86–1.29)

 

20 years since membership

71

0.97 (0.76–1.22)

 

Nonpainters

21

0.77 (0.48–1.18)

 

20 years since membership

12

0.67 (0.34–1.17)

Fu et al., 1996

Shoe-manufacturing workers

 

 

English workers:

 

 

Probable solvent exposure

1

0.25 (0.01–1.37)

 

High solvent exposure

0



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