Reference

Study Population

Exposed Cases

Estimated Relative Risk (95% CI)

Other Organic Solvents

Cohort Studies—Mortality

Boice et al., 1999

Aircraft-manufacturing workers in California

 

 

Tetrachloroethylene, routine exposure

1

0.40 (0.01–2.25)

 

Routine or intermittent exposure

 

 

<1 year of exposure

1

0.46 (0.06–3.48)

 

1–4 years of exposure

4

1.13 (0.38–3.35)

 

≥5 years of exposure

1

0.24 (0.03–1.84)

Blair et al., 1998

Aircraft-maintenance workers in Utah

 

 

Stoddard solvent

 

 

Males

96

1.0 (0.3–3.2)

 

Females

3

1.6 (0.3–8.2)

 

Isopropyl alcohol (males)

4

1.5 (0.4–6.4)

 

Trichloroethane (females)

2

13.2 (2.2–80.4)

 

Acetone

 

 

Males

4

1.6 (0.4–6.7)

 

Females

2

3.8 (0.6–23.8)

 

Toluene

 

 

Males

2

0.9 (0.2–4.8)

 

Females

4

5.0 (1.1–23.1)

 

Methyl ethyl ketone

 

 

Males

1

0.4 (0.1–4.0)

 

Females

3

4.6 (0.9–23.2)

 

Methylene chloride (males)

5

3.4 (0.9–13.2)

Unspecified Mixtures of Organic Solvents

Cohort Studies—Incidence

Lundberg and Milatou-Smith, 1998

Male Swedish paint-industry workers, ever employed

 

 

Incidence

4

3.2 (0.9–8.3)

Berlin et al., 1995

Swedish workers occupationally exposed to solvents

3

2.0 (0.4–5.7)

Lynge et al., 1995

Printing-industry workers in Denmark

 

 

Bookbinders, ever employed

1

1.27 (0.02–7.04)

 

Typographer (printing establishment), ever employed

4

1.14 (0.31–2.93)

Cohort Studies—Mortality

Boice et al., 1999

Aircraft-manufacturing workers in California

 

 

Factory workers, ever exposed

90

1.17 (0.95–1.45)a

 

Mixed solvents, routine exposure

15

0.98 (0.55–1.61)

 

Routine or intermittent exposure

 

 

<1 year of exposure

3

0.34 (0.10–1.14)

 

1–4 years of exposure

13

0.63 (0.32–1.25)

 

≥5 years of exposure

34

0.80 (0.46–1.38)

 

Painter, employed >1 year

4

1.70 (0.46–4.35)

Steenland and Palu, 1999

US painters-union members

 

 

Painters

64

0.97 (0.75–1.24)

 

20-year membership

54

1.01 (0.76–1.32)



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