Reference

Study Population

Exposed Cases

Estimated Relative Risk (95% CI)

Schnatter et al., 1996a

Male Canadian petroleum distribution workers

 

 

By median, 75th, and 90th percentiles

 

 

0.0–0.49 ppm-years

10

1.00

 

0.50–7.99 ppm-years

1

0.22 (0.0–1.82)

 

8.0–19.99 ppm-years

1

0.42 (0.01–3.95)

 

20.0–219.8 ppm-years

2

0.96 (0.09–6.81)

 

Exposure by regulatory standards

 

 

0.00–0.45 ppm-years

10

1.00b

 

>0.45–4.5 ppm-years

1

0.43 (0.0–4.05)

 

4.5–45 ppm-years

1

0.16 (0.0–4.55)

 

≥45 ppm-years

2

1.47 (0.16–13.1)

Rinsky et al., 1987

Male US Pliofilm workers

 

 

Ever exposed

9

3.37 (1.54–6.41)

 

0.001–40 ppm-years

2

1.09 (0.12–3.94)

 

40–200 ppm-years

2

3.22 (0.36–11.65)

 

200–400 ppm-years

2

11.86 (1.33–42.85)

 

>400 ppm-years

3

66.37 (13.34–193.9)

Wong, 1987a,b

Male chemical manufacturing workers

 

 

Entire cohort

7

0.75 (0.30–1.54)

 

Continuously exposed

6

1.35 (0.49–2.95)

 

Cumulative exposure

 

 

<180 ppm-months

2

0.97 (0.12–3.49)

 

180–719 ppm-months

1

0.78 (0.20–4.34)

 

≥720 ppm-months

3

2.76 (0.57–8.06)

Bond et al., 1986

Male chemical workers, ever exposed

 

 

Cohort less those exposed to arsenic, asbestos, or high levels of vinyl chloride

3

1.62 (0.33–4.61)

Rushton and Alderson, 1981

Male employees in eight UK oil refineries, ever exposed

NA

2.33 (0.98–5.56)

Trichloroethylene

Cohort Study—Incidence

Hansen et al., 2001

Biologically monitored Danish workers

 

 

Males

5

1.9 (0.6–4.4)

 

Females

1

3.1 (0.04–18.0)

Cohort Studies—Mortality

Ritz, 1999

White male employees at a uranium-processing plant in Ohio

12

1.09 (0.56–1.91)

Boice et al., 1999

Aircraft-manufacturing workers in California, ever exposed

2

1.05 (0.54–1.84)

Blair et al., 1998

Aircraft-maintenance workers in Utah

 

 

Combined early and recent followup cohort

16

0.6 (0.3–1.2)

 

Men (cumulative exposure)

 

 

No exposure

9

1.0 (0.4–2.9)

 

<5 unit-years

7

1.0 (0.3–3.2)

 

5–25 unit-years

0

 

>25 unit-years

7

1.2 (0.4–3.6)

Morgan et al., 1998

Aerospace workers in Arizona, ever exposed

10

1.05 (0.50–1.93)



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