Reference

Study Population

Exposed Cases

Estimated Relative Risk (95% CI)

Other Specific Organic Solvents

Cohort Study—Incidence

Svensson et al., 1990

Male rotogravure workers in Sweden—toluene

 

 

All exposed

3

1.67 (0.34–4.88)

 

≥5 years of exposure and >10-year latency

3

2.54 (0.52–7.42)

Cohort Studies—Mortality

Boice et al., 1999

Aircraft-manufacturing workers in California

 

 

Ever exposed—tetrachloroethylene

5

1.09 (0.35–2.55)

Dosemeci et al., 1991

Male workers exposed to phenol

 

 

No exposure

7

0.9

 

All exposed

14

0.9 (0.5–1.4)

 

High exposure

1

0.8

 

Medium exposure

5

0.7

 

Low exposure

8

1.0

Case-Control Studies

Costantini et al., 2001

Residents of 12 areas of Italy

 

 

Launderers, dry cleaners, pressers, ever employed

2

3.3 (0.3–32.4)

Aschengrau et al., 1993

Residents of Cape Code, MA—tetrachloroethylene

 

 

Exposure history

 

 

Any

7

1.77 (0.63–4.33)

 

Low

5

1.38 (0.40–3.78)

 

High

2

5.95 (0.58–31.72)

Unspecified Mixtures of Organic Solvents

Cohort Studies—Incidence

Anttila et al., 1998

Finnish workers monitored for exposure to solvents

 

 

Aromatic hydrocarbons, all years

1

0.30 (0.01–1.67)

Lundberg and Milatou-Smith, 1998

Swedish paint-industry workers

 

Incidence, male workers, ≥5 years

3

1.5 (0.3–4.3)

Berlin et al., 1995

Swedish workers occupationally exposed to solvents

 

 

Incidence

6

2.1 (0.8–4.6)

Anttila et al., 1995

Finnish workers exposed to halogenated hydrocarbons

 

 

Ever exposed, male and female for the entire measurement period

5

1.08 (0.35–2.53)

 

Mean personal level

 

 

<100 µmol/L

1

0.39 (0.01–2.19)

 

100+ µmol/L

4

2.65 (0.72–6.78)

Cohort Studies—Mortality

Boice et al., 1999

Aircraft-manufacturing workers in California

 

 

Mixed solvents, ever exposed

28

1.02 (0.68–1.48)

Steenland and Palu, 1999

Painter-union members

 

 

Painters (all members)

138

0.92 (0.78–1.11)

 

Painters (20 years since first union membership)

111

1.11 (0.74–1.08)

Lundberg and Milatou-Smith, 1998

Swedish paint-industry workers

 

Mortality, male workers, ≥5 years

2

1.2 (0.2–4.3)



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement