Reference

Study Population and Cancer Type

Exposed Cases

Estimated Relative Risk (95% CI)

Rushton and Romaniuk, 1996

Male petroleum-distribution workers in the UK—AML (myeloid and monocytic)

 

 

<0.45 ppm-years

7

1

 

0.45–4.49 ppm-years

15

2.17 (0.77–6.09)

 

4.5–44.9 ppm-years

9

2.82 (0.82–9.38)

 

>45 ppm-years

Yin et al., 1996a,b

Chinese factory workers, ever exposed

 

 

Incidence of AML

23

3.1 (1.2–10.7)

 

Incidence of ALL

5

2.8 (0.5–54.5)

Wong, 1995

Male Pliofilm workers in Ohio—AML (myeloid and monocytic)

 

 

<40 ppm-years

1

1.19 (0.03–6.63)

 

40–200 ppm-years

0

0 (0–14.75)

 

200–400 ppm-years

2

27.21 (3.29–98.24)

 

>400 ppm-years

3

98.37 (20.28–287.65)

 

Total

6

5.03 (1.84–10.97)

Crump, 1994

Male Pliofilm workers in Ohio—AML (myeloid and monocytic)

 

 

Total (two cases could not be identified as to type)

8–10

5.0–6.2

 

0–45 ppm-years)

0–2

0.0–2.4

 

45–400 ppm-years

1

2.0 (0.05–10.92)b

 

400–1000 ppm-years

2

9.1 (1.10–32.82)b

 

>1000 ppm-years

5

82.8 (27.00–194.50)b

Case-Control Studies

Albin et al., 2000

Residents of Lund, Sweden—AML

 

 

All exposure levels

39

1.5 (0.89–2.6)

 

Hobby—low levels

28

1.6 (0.89–3.1)

 

Moderate-high levels

11

1.3 (0.52–3.1)

Ciccone et al., 1993

Residents in the Main Hospital of Torino, Italy—AML, CML, MDS; ever exposed

10

1.7 (0.6–5.5)

Richardson et al., 1992

Residents of Paris and Créteil, France—acute leukemia; occupationally exposed

 

 

All exposure levels

22

1.3 (0.8–2.3)

 

High or medium exposure

15

2.8 (1.3–5.9)

Unspecified Mixtures of Organic Solvents

Case-Control Studies

Albin et al., 2000

Residents of Lund, Sweden—AML

 

 

Organic solvents, all exposure levels

88

1.6 (1.1–2.4)

 

Low levels (hobby use)

70

1.5 (1.0–2.3)

 

1–7 years-duration

10

0.72 (0.32–1.6)

 

8–14 years-duration

18

1.5 (0.73–3.1)

 

15–20 years-duration

42

2.1 (1.2–3.7)

 

Moderate-high levels

18

2.3 (1.0–5.0)

 

Moderate for 1–20 years

9

1.6 (0.57–4.3)

 

High for 1–20 years

9

3.9 (1.0–15)

 

Chlorinated solvents

12

0.78 (0.36–1.7)



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