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NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

This study was supported by the Research Corporation under Grant No. GG0066, the Camille and Henry Dreyfus Foundation under Grant No. SG-00-094 and SG-02-025, the National Institutes of Standards and Technology, Grant No. NA1341-01-W-1098, the U.S. Department of Defense under Grant No. MDA-972-01-M-0038, the U.S. Environmental Protection Agency under Grant No. R-82823201, the National Science Foundation under Grant No. CHE-000778, the National Institutes of Health under Contract No. N01-OD-4-2139, and the U.S. Department of Energy under Grant No. DE-FG02-95ER14556. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the views of the organizations or agencies that provided support for the project.

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