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The following HTML text is provided to enhance online readability. Many aspects of typography translate only awkwardly to HTML. Please use the page image as the authoritative form to ensure accuracy. THE NATIONAL ACADEMIES PRESS NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. Support for this project was provided by the Rockefeller Foundation. Any opinions, findings, conclusions, or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the sponsor. International Standard Book Number 0-309-08868-2 Library of Congress Control Number 2003103683 Cover design by Jennifer M. Bishop Copies of this report are available from the Copyright 2003 by the National Academy of Sciences. All rights reserved. Printed in the United States of America
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