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OCR for page 33
Characterizing Exposure ... Final Report are subject to privacy restrictions and, as noted here, it may be difficult to both access them and use the data contained within them. The Guide provides a table delineating available records by the branch of the service that produced them, the record's formal name, and the data available in them. It also suggests a hierarchical order in which to access them, based on the quality and level of detail of the information. Accomplishments Creation of Characterizing Exposure to Agent Orange and Other Herbicides Used in Vietnam: An Epidlemiologist's Guidle to Useful Military Records, a lessons-learned guide to the design and execution of future studies of veterans. PROJECT 4: BIOMARKERS OF TCDD (DIOXIN) EXPOSURE IN VIETNAM VETERANS The focus of this project was the extent to which biologic samples from people are a useful tool in quantifying exposure to herbicides some 25 or more years earlier. The original intent was to analyze the dioxin content of samples drawn from veterans identified through E4 EO] estimates as representing a range of possible exposures, with an oversampling of heavily exposed veterans. The association between the measurements and EO] estimates was to be evaluated, as was the correspondence between these data and self-reports of herbicide exposure. The researchers intended to use a screening test based on a recombinant cell-bioassay system (CALUX) (Garrison et al., 1996; Murk et al., 1997). The assay would be run on split samples that represented an appropriate range of concentrations and of dioxin congeners to test the sensitivity and specificity of the screening method in this application. 3:3