that activates the myometrium. A second hypothesis is that through stimulation of the formation of metalloproteinases, cytokines degrade proteins, which will lead to preterm rupture of membranes. Presently, there are a number of unanswered questions regarding this hypothesis. Some participants suggested that this is an area in need of additional research.

The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement