. "3. PReterm Birth - Brief Summary of Biological Pathways." The Role of Environmental Hazards in Premature Birth: Workshop Summary. Washington, DC: The National Academies Press, 2003.
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The Role of Environmental Hazards in Premature Birth: Workshop Summary
that activates the myometrium. A second hypothesis is that through stimulation of the formation of metalloproteinases, cytokines degrade proteins, which will lead to preterm rupture of membranes. Presently, there are a number of unanswered questions regarding this hypothesis. Some participants suggested that this is an area in need of additional research.