E
Acronyms


AACE

American Association of Clinical Endocrinologists

ADL

activities of daily living

AIDS

acquired immunodeficiency syndrome

AR

androgen receptor

AUA

American Urological Association

AUR

acute urinary retention


BDI

Beck Depression Inventory

BLSA

Baltimore Longitudinal Study of Aging

BMD

bone mineral density

BMI

body mass index

BOP

N-nitrosobis(2-oxypropyl)amine

BP

blood pressure

BPH

benign prostatic hypertrophy

BT

bioavailable testosterone


CAD

coronary artery disease

CGI

Clinical Global Impression score

CI

confidence interval


DBP

diastolic blood pressure

DHEA

dehydroepiandrosterone

DHEAS

dehydroepiandrosterone-sulfate

DHT

dihydrotestosterone

DRE

digital rectal examination



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OCR for page 202
Testosterone and Aging: Clinical Research Directions E Acronyms AACE American Association of Clinical Endocrinologists ADL activities of daily living AIDS acquired immunodeficiency syndrome AR androgen receptor AUA American Urological Association AUR acute urinary retention BDI Beck Depression Inventory BLSA Baltimore Longitudinal Study of Aging BMD bone mineral density BMI body mass index BOP N-nitrosobis(2-oxypropyl)amine BP blood pressure BPH benign prostatic hypertrophy BT bioavailable testosterone CAD coronary artery disease CGI Clinical Global Impression score CI confidence interval DBP diastolic blood pressure DHEA dehydroepiandrosterone DHEAS dehydroepiandrosterone-sulfate DHT dihydrotestosterone DRE digital rectal examination

OCR for page 202
Testosterone and Aging: Clinical Research Directions E2 estradiol ED erectile dysfunction ESTEEM Efficacy and Safety of Testosterone in Elderly Men Trial FDA Food and Drug Administration FICSIT Frailty and Injuries: Cooperative Studies of Intervention Techniques FIM Functional Independence Measure FSFI Female Sexual Function Index FSH follicle stimulating hormone FT free testosterone FTI free testosterone index GDS-SF Geriatric Depression Score Short Form GH growth hormone GnRH gonadotropin-releasing hormone Ham-D Hamilton Depression Rating Scale HDL high-density lipoprotein HIV human immunodeficiency virus HRQoL health-related quality of life IADL instrumental activities of daily living IGF insulin-like growth factor IGFBP insulin-like growth factor binding protein IIEF International Index of Erectile Functioning IM intramuscular IMT intima-media thickness IOM Institute of Medicine IPSS International Prostate Symptom Scale IRB institutional review board LDL low-density lipoprotein LH luteinizing hormone LHRH luteinizing hormone-releasing hormone Lp(a) lipoprotein a MMAS Massachusetts Male Aging Study MRFIT Multiple Risk Factor Intervention Trial MNU N-methyl-N-nitrosourea NA not applicable NCI National Cancer Institute

OCR for page 202
Testosterone and Aging: Clinical Research Directions NIA National Institute on Aging NIH National Institutes of Health NR not reported OR odds ratio PAI plasminogen activator inhibitor PCPT Prostate Cancer Prevention Trial PGWB Psychological General Well-Being scale PIN prostate intraepithelial neoplasia PLESS Proscar Long-term Efficacy and Safety Study POMS Profile of Mood States PSA prostate-specific antigen PSDI Positive Symptom Distress Index Q-LES-Q Endicott Quality of Life Enjoyment and Satisfaction Questionnaire RF risk factor RR relative risk RTI Research Triangle Institute SARMs selective androgen receptor modulators SBP systolic blood pressure SD standard deviation SF-36 Short Form 36 item questionnaire SHBG sex hormone-binding globulin SI Système International T testosterone TC testosterone cypionate TE testosterone enanthate TG triglycerides TT total testosterone TU testosterone undecanoate WHI Women’s Health Initiative