National Academies Press: OpenBook

Testosterone and Aging: Clinical Research Directions (2004)

Chapter: Appendix E: Acronyms

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Suggested Citation:"Appendix E: Acronyms." Institute of Medicine. 2004. Testosterone and Aging: Clinical Research Directions. Washington, DC: The National Academies Press. doi: 10.17226/10852.
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E
Acronyms


AACE

American Association of Clinical Endocrinologists

ADL

activities of daily living

AIDS

acquired immunodeficiency syndrome

AR

androgen receptor

AUA

American Urological Association

AUR

acute urinary retention


BDI

Beck Depression Inventory

BLSA

Baltimore Longitudinal Study of Aging

BMD

bone mineral density

BMI

body mass index

BOP

N-nitrosobis(2-oxypropyl)amine

BP

blood pressure

BPH

benign prostatic hypertrophy

BT

bioavailable testosterone


CAD

coronary artery disease

CGI

Clinical Global Impression score

CI

confidence interval


DBP

diastolic blood pressure

DHEA

dehydroepiandrosterone

DHEAS

dehydroepiandrosterone-sulfate

DHT

dihydrotestosterone

DRE

digital rectal examination

Suggested Citation:"Appendix E: Acronyms." Institute of Medicine. 2004. Testosterone and Aging: Clinical Research Directions. Washington, DC: The National Academies Press. doi: 10.17226/10852.
×

E2

estradiol

ED

erectile dysfunction

ESTEEM

Efficacy and Safety of Testosterone in Elderly Men Trial


FDA

Food and Drug Administration

FICSIT

Frailty and Injuries: Cooperative Studies of Intervention Techniques

FIM

Functional Independence Measure

FSFI

Female Sexual Function Index

FSH

follicle stimulating hormone

FT

free testosterone

FTI

free testosterone index


GDS-SF

Geriatric Depression Score Short Form

GH

growth hormone

GnRH

gonadotropin-releasing hormone


Ham-D

Hamilton Depression Rating Scale

HDL

high-density lipoprotein

HIV

human immunodeficiency virus

HRQoL

health-related quality of life


IADL

instrumental activities of daily living

IGF

insulin-like growth factor

IGFBP

insulin-like growth factor binding protein

IIEF

International Index of Erectile Functioning

IM

intramuscular

IMT

intima-media thickness

IOM

Institute of Medicine

IPSS

International Prostate Symptom Scale

IRB

institutional review board

LDL

low-density lipoprotein

LH

luteinizing hormone

LHRH

luteinizing hormone-releasing hormone

Lp(a)

lipoprotein a


MMAS

Massachusetts Male Aging Study

MRFIT

Multiple Risk Factor Intervention Trial

MNU

N-methyl-N-nitrosourea


NA

not applicable

NCI

National Cancer Institute

Suggested Citation:"Appendix E: Acronyms." Institute of Medicine. 2004. Testosterone and Aging: Clinical Research Directions. Washington, DC: The National Academies Press. doi: 10.17226/10852.
×

NIA

National Institute on Aging

NIH

National Institutes of Health

NR

not reported


OR

odds ratio


PAI

plasminogen activator inhibitor

PCPT

Prostate Cancer Prevention Trial

PGWB

Psychological General Well-Being scale

PIN

prostate intraepithelial neoplasia

PLESS

Proscar Long-term Efficacy and Safety Study

POMS

Profile of Mood States

PSA

prostate-specific antigen

PSDI

Positive Symptom Distress Index


Q-LES-Q

Endicott Quality of Life Enjoyment and Satisfaction Questionnaire


RF

risk factor

RR

relative risk

RTI

Research Triangle Institute


SARMs

selective androgen receptor modulators

SBP

systolic blood pressure

SD

standard deviation

SF-36

Short Form 36 item questionnaire

SHBG

sex hormone-binding globulin

SI

Système International


T

testosterone

TC

testosterone cypionate

TE

testosterone enanthate

TG

triglycerides

TT

total testosterone

TU

testosterone undecanoate


WHI

Women’s Health Initiative

Suggested Citation:"Appendix E: Acronyms." Institute of Medicine. 2004. Testosterone and Aging: Clinical Research Directions. Washington, DC: The National Academies Press. doi: 10.17226/10852.
×
Page 202
Suggested Citation:"Appendix E: Acronyms." Institute of Medicine. 2004. Testosterone and Aging: Clinical Research Directions. Washington, DC: The National Academies Press. doi: 10.17226/10852.
×
Page 203
Suggested Citation:"Appendix E: Acronyms." Institute of Medicine. 2004. Testosterone and Aging: Clinical Research Directions. Washington, DC: The National Academies Press. doi: 10.17226/10852.
×
Page 204
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Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an “antiaging tonic,” testosterone’s reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an increase in the number of middle-aged and older men using testosterone and the lack of scientific data on the effect it may have on aging males. Studies of testosterone replacement therapy in older men have generally been of short duration, involving small numbers of participants and often lacking adequate controls. Testosterone and Aging weighs the options of future research directions, examines the risks and benefits of testosterone replacement therapy, assesses the potential public health impact of such therapy in the United States, and considers ethical issues related to the conduct of clinical trials. Testosterone therapy remains an attractive option to many men even as speculation abounds regarding its potential.

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