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NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

Support for this project was provided by the National Institute on Aging and the National Cancer Institute. The views presented in this report are those of the Institute of Medicine Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy and are not necessarily those of the funding agencies.

Library of Congress Cataloging-in-Publication Data

Testosterone and aging : clinical research directions / Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy, Board on Health Sciences Policy ; Catharyn T. Liverman, Dan G. Blazer, editors.

p. ; cm.

Includes bibliographical references.

ISBN 0-309-09063-6 (pbk.); 0-309-52720-1 (PDF)

1. Longevity. 2. Aging—Prevention. 3. Testosterone—Physiological effect.

[DNLM: 1. Aging—drug effects. 2. Testosterone—physiology. 3. Testosterone—therapeutic use—Aged. WT 104 T3455 2004] I. Liverman, Catharyn T. II. Blazer, Dan G. (Dan German), 1944- III. National Research Council (U.S.). Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy.

RA776.75.T45 2004

612.6’8—dc22

2003026323

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