. "5 Categories of Scientific Evidence--Animal Data." Dietary Supplements: A Framework for Evaluating Safety. Washington, DC: The National Academies Press, 2005.
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Dietary Supplements: A Framework for Evaluating Safety
As a general guideline, human intakes that exceed one-one hundredth (0.01) of animal doses that produce Category A effects (see Table 5-1) should be considered to represent a significant risk to human health. Human intakes that exceed one-tenth (0.1) of the animal doses that produce Category B effects should be considered to represent a significant risk to human health.
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