Dietary Supplements: A Framework for Evaluating Safety

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Dietary Supplements: A Framework for Evaluating Safety (2005)
Institute of Medicine (IOM)

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. "6 Categories of Scientific Evidence--Information About Related Substances." Dietary Supplements: A Framework for Evaluating Safety. Washington, DC: The National Academies Press, 2005.

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Dietary Supplements: A Framework for Evaluating Safety

Primary Genera of Concern	Family	Compounds and Compound Classes Implicated in Toxicity
Ligustrum	Oleaceae	Unknown
Lobelia	Campanulaceae	Piperidine alkaloids
Lolium	Poaceae	Ergot alkaloids^c Penitrem alkaloids^c Selenium accumulation (Selenium is acquired from Seleniferous soils, not funga)
Lupinus	Fabaceae	Quinolizidine alkaloids
Lycopersicon^b	Solanaceae	Steroidal alkaloids Polyhydroxy alkaloids (calystegines)
Lyonia	Ericaceae	Lyoniatoxin
Macrozamia	Zamiaceae	Methyl azoxymethanol glycosides (i.e., macrozamin)
Manihot^b	Euphorbiaceae	Cyanogenic glycosides
Melilotus^b	Fabaceae	Dicoumarol
Myristica^b	Myristicaceae	Safrole
Narcissus	Amaryllidaceae	Isoquinoline alkaloids
Nerium	Apocynaceae	Cardiac glycosides
Nicotiana	Solanaceae	Nicotine alkaloids
Nolina	Liliaceae	Unknown
Ornithogalum	Liliaceae	Colchicine
Oxytropis	Fabaceae	Polyhydroxy alkaloids (swainsonine)
Pachyrhizus^b	Fabaceae	Unknown
Packera	Asteraceae	Pyrrolizidine alkaloids
Papaver	Papaveraceae	Isoquinoline alkaloids Morphinan alkaloids
Pedicularis	Scrophulariaceae	Pyrrolizidine alkaloids
Petasites	Asteraceae	Pyrrolizidine alkaloids
Phaseolus^b	Fabaceae	Cyanogenic glycoside (phaseolunatin)