Dietary Supplements: A Framework for Evaluating Safety

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Dietary Supplements: A Framework for Evaluating Safety (2005)
Institute of Medicine (IOM)

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. "6 Categories of Scientific Evidence--Information About Related Substances." Dietary Supplements: A Framework for Evaluating Safety. Washington, DC: The National Academies Press, 2005.

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Dietary Supplements: A Framework for Evaluating Safety

Primary Genera of Concern	Family	Compounds and Compound Classes Implicated in Toxicity
Secale^b	Poaceae	Nitrate accumulation, ergot alkaloids^c
Senecio	Asteraceae	Pyrrolizidine alkaloids
Sesbania	Fabaceae	Quinolizidine alkaloids
Solanum^b	Solanaceae	Steroidal alkaloids Polyhydroxyalkaloids (calystegines)
Solidago	Asteraceae	Unknown
Sophora	Fabaceae	Quinolizidine alkaloids
Sorghum^b	Poaceae	Cyanogenic glycosides, nitrate
Spartium	Fabaceae	Sparteine
Strelitzia	Musaceae	Phenalenones
Strychnos	Loganiaceae	Strychnine
Symphytum	Boraginaceae	Pyrrolizidine alkaloids
Tanacetum	Asteraceae	Unknown
Taxus	Taxaceae	Taxoids
Tetradymia	Asteraceae	Furanoeremophilanes
Teucrium	Lamiaceae	Diterpenes (?)
Thevetia	Apocynaceae	Cardiac glycosides
Toxicodendron	Anacardiaceae	Urushiols
Trichodesma	Asteraceae	Pyrrolizidine alkaloids
Trifolium^b	Fabaceae	Coumestrol Isoflavones
Triglochin	Juncaginaceae	Cyanogenic glycosides
Tripterygium	Celastraceae	Diterpenes
Tussilago	Asteraceae	Pyrrolizidine alkaloids
Urginea	Liliaceae	Cardiac glycosides
Veratrum	Liliaceae	Steroidal alkaloids
Vicia	Fabaceae	Aminobutyric and aminopropionic acids and nitriles
Wisteria	Fabaceae	Canavanine
Xanthium	Asteraceae	Carboxyatractyloside
Zamia	Zamiaceae