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Dietary Supplements: A Framework for Evaluating Safety
D.Data Gaps and Future Research Recommended
Additional phytochemical analyses to identify the biologically active components should be a high priority. Once biologically active components are identified, further biological evaluation should be conducted. Safety concerns should be revisited upon identification of additional components.
There is a need to establish the mechanism of action of saw palmetto preparations.
There are insufficient data to conclude that there are no drug interactions between saw palmetto preparations and conventional prescription drugs.
Studies to establish the effects of saw palmetto products on bleeding times could shed additional light on the possible causal relationship of saw palmetto to the single clinical case report of excessive bleeding during surgery.
Studies could shed light on the possibility of detrimental effects on the fetus.
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